MetaQuery: quantitative analysis of the human gut microbiome

Results

Estimated gene abundances and results from statistical analyses

Job details:

Submission date: 2019-12-14 00:40:59 PST
Job id & description: 1560, 4-hydroxybenzoate coa ligase
Query type: protein
Count queries & homologs: 1, 2
Min % identity & max e-value: 30%, 1e-5
Min % query & target coverage: 70%, 70%

Click here to download results

Table of contents:


Gut microbiome genes homologous to your query gene:

query_id target_id status kegg eggnog phylum genus query_cov target_cov percent_identity
sp|Q53005|4HBCL_RHOPA615342Lack 5'-endK01895COG0365unknownunknown75.5170.3432.22
sp|Q53005|4HBCL_RHOPA1297210Lack 5'-endK01895COG0365unknownunknown77.7497.0530.18
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The abundance of your query across gut microbiome samples:




The prevalence of your query across gut microbiome samples:




Taxonomic groups correlated with your query gene:

tax_level tax_name spearman_rho pvalue qvalue
genusPseudoflavonifractor0.5042.77e-1216.54e-119
speciesPseudoflavonifractor_capillosus0.5042.77e-1216.54e-119
speciesSubdoligranulum_unclassified0.4935.06e-1157.96e-113
genusSubdoligranulum0.4921.65e-1141.95e-112
speciesEubacterium_siraeum0.4546.64e-966.27e-94
genusMethanobrevibacter0.456.37e-945.01e-92
speciesMethanobrevibacter_smithii0.457.71e-945.19e-92
classMethanobacteria0.451.1e-935.19e-92
orderMethanobacteriales0.451.1e-935.19e-92
familyMethanobacteriaceae0.451.1e-935.19e-92
phylumEuryarchaeota0.4471.48e-926.35e-91
speciesAnaerotruncus_unclassified0.4345.81e-872.29e-85
genusRuminococcaceae_noname0.3751.34e-634.52e-62
speciesRuminococcaceae_bacterium_D160.3751.34e-634.52e-62
speciesClostridium_leptum0.3627.7e-592.42e-57
phylumVerrucomicrobia0.3551.18e-562.65e-55
classVerrucomicrobiae0.3551.18e-562.65e-55
orderVerrucomicrobiales0.3551.18e-562.65e-55
familyVerrucomicrobiaceae0.3551.18e-562.65e-55
genusAkkermansia0.3551.18e-562.65e-55
speciesAkkermansia_muciniphila0.3551.18e-562.65e-55
genusAnaerotruncus0.3535.95e-561.28e-54
familyRuminococcaceae0.3391.17e-512.4e-50
speciesErysipelotrichaceae_bacterium_21_30.3361.09e-502.14e-49
speciesLachnospiraceae_bacterium_7_1_58FAA0.3352.92e-505.51e-49
speciesMethanobrevibacter_unclassified0.3246.91e-471.25e-45
familyBacteroidales_noname0.316.92e-431.13e-41
genusBacteroidales_noname0.316.92e-431.13e-41
speciesBacteroidales_bacterium_ph80.316.92e-431.13e-41
speciesCollinsella_aerofaciens0.3099.95e-431.57e-41
speciesRuminococcus_gnavus-0.3051.91e-412.91e-40
genusCoprococcus0.3011.57e-402.32e-39
genusCollinsella0.2988.71e-401.25e-38
speciesCoprococcus_catus0.2919.59e-381.33e-36
genusButyrivibrio0.2892.51e-373.34e-36
classClostridia0.2892.62e-373.34e-36
orderClostridiales0.2892.62e-373.34e-36
speciesLachnospiraceae_bacterium_3_1_57FAA_CT10.2838.22e-361e-34
speciesAlistipes_senegalensis0.2838.26e-361e-34
genusBarnesiella0.2821.3e-351.5e-34
speciesBarnesiella_intestinihominis0.2821.3e-351.5e-34
orderCoriobacteriales0.2813.74e-354.11e-34
familyCoriobacteriaceae0.2813.74e-354.11e-34
speciesBifidobacterium_adolescentis0.2676.7e-327.19e-31
speciesDorea_longicatena0.2669.53e-321e-30
speciesLachnospiraceae_bacterium_3_1_46FAA0.2627.99e-318.2e-30
genusAdlercreutzia0.2611.53e-301.5e-29
speciesAdlercreutzia_equolifaciens0.2611.53e-301.5e-29
genusVeillonella-0.2588.46e-308.15e-29
familyOxalobacteraceae0.2571.75e-291.65e-28
genusOxalobacter0.2562.04e-291.85e-28
speciesOxalobacter_formigenes0.2562.04e-291.85e-28
speciesMitsuokella_unclassified0.2553.58e-293.19e-28
speciesEubacterium_hallii0.254.68e-284.09e-27
genusKlebsiella-0.256.23e-285.35e-27
speciesOlsenella_unclassified0.2497.23e-286.09e-27
genusMitsuokella0.2472.21e-271.83e-26
speciesKlebsiella_pneumoniae-0.2463.27e-272.66e-26
speciesVeillonella_unclassified-0.2431.92e-261.54e-25
speciesCoprococcus_comes0.2422.22e-261.75e-25
genusDorea0.247.41e-265.73e-25
genusHaemophilus-0.2365.25e-254e-24
speciesVeillonella_parvula-0.2356.28e-254.71e-24
speciesHaemophilus_parainfluenzae-0.2349.47e-256.98e-24
speciesAlistipes_onderdonkii0.2332.19e-241.59e-23
genusOlsenella0.2322.58e-241.85e-23
orderPasteurellales-0.2323.06e-242.12e-23
familyPasteurellaceae-0.2323.06e-242.12e-23
familyFusobacteriaceae-0.2291.29e-238.82e-23
genusDesulfovibrio0.2282.01e-231.36e-22
phylumFusobacteria-0.2273.12e-232.02e-22
classFusobacteriia-0.2273.12e-232.02e-22
orderFusobacteriales-0.2273.12e-232.02e-22
classBacteroidia-0.2273.39e-232.11e-22
orderBacteroidales-0.2273.39e-232.11e-22
phylumBacteroidetes-0.2273.4e-232.11e-22
genusFusobacterium-0.2257.3e-234.47e-22
speciesOscillibacter_unclassified0.2231.52e-229.2e-22
speciesAlistipes_indistinctus0.2231.72e-221.03e-21
speciesEubacterium_ramulus0.2222.34e-221.38e-21
phylumFirmicutes0.2222.37e-221.38e-21
familyBacteroidaceae-0.2213.61e-222.05e-21
genusBacteroides-0.2213.61e-222.05e-21
speciesDesulfovibrio_desulfuricans0.2198.04e-224.52e-21
speciesEubacterium_cylindroides0.2181.56e-218.66e-21
speciesRuminococcus_obeum0.2163.07e-211.68e-20
speciesAlistipes_sp_AP110.2131.4e-207.6e-20
familyRikenellaceae0.2121.71e-209.07e-20
genusAlistipes0.2121.71e-209.07e-20
genusOdoribacter0.2121.99e-201.04e-19
familyOscillospiraceae0.2113.51e-201.8e-19
genusOscillibacter0.2113.51e-201.8e-19
speciesVeillonella_dispar-0.2098.15e-204.14e-19
speciesBacteroides_stercoris-0.2071.66e-198.34e-19
speciesButyrivibrio_crossotus0.2062.72e-191.35e-18
speciesVeillonella_atypica-0.2052.86e-191.41e-18
genusRuminococcus0.2054.18e-192.03e-18
speciesClostridium_nexile-0.2021.31e-186.31e-18
speciesCoprococcus_sp_ART55_10.2011.81e-188.63e-18
speciesCoprobacillus_unclassified-0.22.86e-181.35e-17
genusCoprobacter0.1993.13e-181.45e-17
speciesCoprobacter_fastidiosus0.1993.13e-181.45e-17
speciesMegamonas_unclassified-0.1993.36e-181.54e-17
phylumActinobacteria0.1993.82e-181.72e-17
classActinobacteria0.1993.82e-181.72e-17
genusMegamonas-0.1994.33e-181.93e-17
speciesRoseburia_hominis0.1977.8e-183.44e-17
speciesAlistipes_finegoldii0.1952.02e-178.83e-17
familySiphoviridae0.1952.04e-178.83e-17
genusErysipelotrichaceae_noname0.199.98e-174.28e-16
speciesRuminococcus_champanellensis0.1891.43e-166.08e-16
classErysipelotrichia0.1891.55e-166.42e-16
orderErysipelotrichales0.1891.55e-166.42e-16
familyErysipelotrichaceae0.1891.55e-166.42e-16
speciesStreptococcus_thermophilus0.1882.37e-169.73e-16
genusC2likevirus0.1882.46e-161e-15
familyEubacteriaceae0.1882.52e-161.02e-15
genusEubacterium0.1882.61e-161.04e-15
speciesFusobacterium_mortiferum-0.1882.66e-161.06e-15
speciesOdoribacter_splanchnicus0.1873.58e-161.41e-15
speciesC2likevirus_unclassified0.1864.87e-161.9e-15
speciesRuminococcus_lactaris0.1849.66e-163.74e-15
genusMethanosphaera0.1841e-153.81e-15
speciesMethanosphaera_stadtmanae0.1841e-153.81e-15
speciesSubdoligranulum_sp_4_3_54A2FAA0.1841.19e-154.49e-15
classGammaproteobacteria-0.1813.68e-151.38e-14
speciesRuminococcus_bromii0.185.05e-151.88e-14
speciesAlistipes_shahii0.1781.04e-143.84e-14
speciesAnaerostipes_hadrus0.1771.1e-144.02e-14
speciesClostridium_sp_L2_500.1752.79e-141.01e-13
speciesMegasphaera_micronuciformis-0.1743.71e-141.34e-13
speciesDorea_formicigenerans0.1743.98e-141.42e-13
speciesEubacterium_biforme0.1735e-141.77e-13
phylumProteobacteria-0.1728.07e-142.84e-13
genusGordonibacter0.1691.67e-135.8e-13
speciesGordonibacter_pamelaeae0.1691.67e-135.8e-13
familyVeillonellaceae-0.1673.71e-131.28e-12
speciesLachnospiraceae_bacterium_9_1_43BFAA-0.1673.8e-131.3e-12
speciesButyrivibrio_unclassified0.1664.8e-131.63e-12
speciesHoldemania_filiformis0.1657.04e-132.37e-12
speciesRuminococcus_sp_5_1_39BFAA0.1594.45e-121.49e-11
speciesBacteroides_thetaiotaomicron-0.1594.59e-121.53e-11
speciesClostridium_bolteae-0.1579.18e-123.03e-11
genusCoprobacillus-0.1579.43e-123.09e-11
speciesEubacterium_ventriosum0.1561.09e-113.55e-11
speciesBacteroides_ovatus-0.1561.13e-113.65e-11
speciesClostridium_ramosum-0.1561.34e-114.3e-11
genusMegasphaera-0.1551.4e-114.46e-11
speciesBifidobacterium_longum0.1551.66e-115.26e-11
speciesRuminococcus_torques0.1551.81e-115.7e-11
speciesAlistipes_putredinis0.156.46e-112.02e-10
orderCaudovirales0.1498.64e-112.68e-10
genusSiphoviridae_noname0.1491.04e-103.21e-10
speciesBacteroides_cellulosilyticus0.1481.16e-103.56e-10
familyPorphyromonadaceae0.1481.29e-103.93e-10
speciesClostridium_citroniae-0.1481.43e-104.33e-10
genusBifidobacterium0.1471.51e-104.54e-10
orderBifidobacteriales0.1471.56e-104.63e-10
familyBifidobacteriaceae0.1471.56e-104.63e-10
speciesEubacterium_rectale0.1452.9e-108.55e-10
phylumViruses_noname0.1444e-101.17e-09
classViruses_noname0.1444e-101.17e-09
speciesBifidobacterium_pseudocatenulatum-0.1434.7e-101.36e-09
speciesFusobacterium_ulcerans-0.1434.99e-101.44e-09
speciesFusobacterium_varium-0.1426.67e-101.91e-09
speciesPrevotella_stercorea-0.141.19e-093.38e-09
speciesEnterobacter_cloacae-0.141.23e-093.48e-09
genusEnterobacter-0.1382.17e-096.1e-09
speciesLactobacillus_salivarius-0.1372.64e-097.37e-09
orderEnterobacteriales-0.1372.69e-097.43e-09
familyEnterobacteriaceae-0.1372.69e-097.43e-09
speciesLachnospiraceae_bacterium_6_1_63FAA-0.1363.98e-091.09e-08
speciesMegamonas_rupellensis-0.1354.45e-091.21e-08
speciesErysipelotrichaceae_bacterium_6_1_450.1346.3e-091.71e-08
speciesClostridium_symbiosum-0.1311.27e-083.43e-08
speciesMegamonas_hypermegale-0.1311.3e-083.49e-08
speciesBacteroides_pectinophilus0.1311.41e-083.76e-08
speciesErysipelotrichaceae_bacterium_2_2_44A0.1292.38e-086.31e-08
genusHoldemania0.1265.08e-081.34e-07
speciesLachnospiraceae_bacterium_2_1_58FAA-0.1255.29e-081.39e-07
speciesEggerthella_unclassified-0.1255.5e-081.43e-07
speciesBlautia_hydrogenotrophica0.1247.84e-082.03e-07
speciesRoseburia_unclassified0.1239.64e-082.49e-07
speciesPrevotella_buccae-0.1221.12e-072.87e-07
speciesAnaerostipes_unclassified-0.1221.26e-073.21e-07
speciesMegamonas_funiformis-0.1211.54e-073.91e-07
speciesClostridium_perfringens-0.1211.63e-074.11e-07
speciesLactococcus_lactis0.122.04e-075.12e-07
speciesBacteroides_xylanisolvens-0.1192.28e-075.69e-07
speciesPorphyromonas_asaccharolytica0.1192.39e-075.94e-07
speciesStreptococcus_mitis_oralis_pneumoniae-0.1192.48e-076.13e-07
genusAnaerostipes0.1192.63e-076.47e-07
genusTuricibacter0.1182.82e-076.9e-07
speciesPrevotella_copri-0.1182.97e-077.23e-07
genusPrevotella-0.1182.99e-077.24e-07
speciesBacteroides_plebeius-0.1183.04e-077.32e-07
speciesTuricibacter_unclassified0.1183.17e-077.6e-07
speciesClostridiales_bacterium_1_7_47FAA-0.1173.48e-078.3e-07
speciesOdoribacter_laneus0.1165.22e-071.24e-06
familyLachnospiraceae0.1155.6e-071.32e-06
genusWeissella-0.1155.76e-071.35e-06
genusCatenibacterium0.1156.56e-071.53e-06
speciesCatenibacterium_mitsuokai0.1156.56e-071.53e-06
genusPorphyromonas0.1138.88e-072.05e-06
speciesBlautia_producta-0.1139.53e-072.19e-06
genusEggerthella-0.1139.65e-072.21e-06
speciesCampylobacter_concisus-0.1121.26e-062.87e-06
speciesBacteroides_salanitronis0.1111.44e-063.27e-06
genusFlavonifractor-0.1111.46e-063.28e-06
speciesFlavonifractor_plautii-0.1111.46e-063.28e-06
speciesLactococcus_phage_P6800.112.06e-064.61e-06
speciesParabacteroides_merdae0.1092.21e-064.92e-06
classNegativicutes-0.1082.8e-066.18e-06
orderSelenomonadales-0.1082.8e-066.18e-06
genusActinobacillus-0.1064.14e-069e-06
speciesActinobacillus_unclassified-0.1064.14e-069e-06
speciesAlistipes_sp_HGB50.1064.14e-069e-06
speciesLachnospiraceae_bacterium_2_1_46FAA-0.1064.71e-061.02e-05
speciesLactobacillus_mucosae-0.1055.13e-061.11e-05
speciesCoprococcus_eutactus0.1046.2e-061.33e-05
speciesDesulfovibrio_piger0.1037.44e-061.59e-05
genusEscherichia-0.1038.53e-061.81e-05
familyAcidaminococcaceae0.1029.03e-061.91e-05
speciesKlebsiella_unclassified-0.1021.01e-052.13e-05
speciesEscherichia_coli-0.1011.1e-052.31e-05
speciesFusobacterium_nucleatum-0.1011.17e-052.44e-05
genusLactococcus0.1011.29e-052.68e-05
genusAggregatibacter-0.1011.31e-052.71e-05
speciesClostridium_clostridioforme-0.11.36e-052.8e-05
speciesBacteroides_uniformis0.0991.91e-053.92e-05
speciesStreptococcus_salivarius-0.0982.2e-054.5e-05
speciesTuricibacter_sanguinis0.0982.28e-054.64e-05
speciesBacteroides_oleiciplenus-0.0972.59e-055.25e-05
speciesPropionibacterium_freudenreichii0.0972.77e-055.59e-05
classDeltaproteobacteria0.0962.94e-055.86e-05
orderDesulfovibrionales0.0962.94e-055.86e-05
familyDesulfovibrionaceae0.0962.94e-055.86e-05
speciesStreptococcus_australis-0.0953.9e-057.73e-05
speciesStreptococcus_anginosus-0.0954.25e-058.39e-05
speciesRuminococcus_callidus0.0944.39e-058.63e-05
speciesAggregatibacter_segnis-0.0944.41e-058.64e-05
speciesBacteroides_fragilis-0.0935.62e-050.00011
speciesWeissella_confusa-0.0927.15e-050.000139
genusPhascolarctobacterium0.0917.65e-050.000147
speciesPhascolarctobacterium_succinatutens0.0917.65e-050.000147
speciesHoldemania_unclassified0.0917.78e-050.000149
genusCoriobacteriaceae_noname0.0890.0001140.000218
genusAcidaminococcaceae_unclassified0.0890.0001250.000238
familyMyoviridae-0.0880.0001340.000254
speciesCoriobacteriaceae_bacterium_phI0.0880.0001410.000266
speciesWeissella_cibaria-0.0860.0001860.00035
genusCitrobacter-0.0840.0002820.000528
speciesBifidobacterium_animalis0.0840.0002870.000535
familyBacillales_noname-0.0830.0003480.000644
genusGemella-0.0830.0003480.000644
speciesEubacterium_eligens0.0820.0003660.000675
orderBacillales-0.0820.0003690.000678
speciesHaemophilus_paraphrohaemolyticus-0.0820.0003730.000682
speciesBifidobacterium_breve-0.0820.000380.000693
speciesEubacterium_limosum0.0810.0004910.000891
speciesCitrobacter_freundii-0.080.0005340.000966
speciesLachnospiraceae_bacterium_1_4_56FAA-0.080.0005540.000998
speciesStreptococcus_gordonii-0.080.0005720.00103
speciesSutterella_wadsworthensis0.080.0005780.00103
speciesCitrobacter_unclassified-0.0790.0006030.00107
genusPantoea-0.0780.0007410.00131
speciesPantoea_unclassified-0.0780.0007410.00131
speciesStreptococcus_sanguinis-0.0780.0007720.00136
speciesOdoribacter_unclassified0.0780.0007920.00139
speciesLactobacillus_casei_paracasei0.0770.0008540.00149
classBetaproteobacteria-0.0770.0009190.0016
speciesMegasphaera_unclassified-0.0770.0009250.00161
speciesLeuconostoc_lactis-0.0760.0009520.00165
genusPropionibacterium0.0760.0009640.00166
speciesEnterobacter_aerogenes-0.0750.001140.00196
speciesPeptostreptococcaceae_noname_unclassified0.0740.00140.00239
speciesParabacteroides_goldsteinii0.0730.001560.00266
orderBurkholderiales-0.0730.001630.00277
speciesLactobacillus_sanfranciscensis-0.0710.001980.00335
speciesHaemophilus_sputorum-0.0710.001990.00335
speciesStreptococcus_infantarius-0.070.002470.00415
genusRoseburia-0.070.002610.00437
speciesBifidobacterium_bifidum0.0690.002710.00452
familyPropionibacteriaceae0.0690.002770.0046
speciesBacteroides_massiliensis-0.0680.003420.00566
speciesBacteroides_finegoldii-0.0680.003490.00576
speciesAlistipes_unclassified0.0670.003510.00577
speciesBilophila_wadsworthia0.0670.003540.0058
genusStreptococcus-0.0670.003560.00581
speciesBifidobacterium_catenulatum0.0670.003650.00594
familyPrevotellaceae-0.0670.003960.00642
familySutterellaceae-0.0660.004310.00697
genusSutterella0.0660.004470.0072
speciesSutterella_parvirubra-0.0650.005040.00809
speciesClostridium_sp_ATCC_BAA_442-0.0650.005150.00824
genusBlautia0.0640.0060.00957
speciesBacteroides_coprocola-0.0630.006690.0106
speciesBacteroides_nordii-0.0620.007580.012
speciesParabacteroides_sp_D130.0610.007990.0126
speciesClostridium_spiroforme0.0610.008030.0126
speciesStreptococcus_pasteurianus-0.0610.008810.0138
familyStreptococcaceae-0.060.009640.0151
speciesPorphyromonas_uenonis0.060.009820.0153
speciesPeptostreptococcus_anaerobius0.0590.01010.0157
speciesLactococcus_phage_phi70.0590.01020.0158
speciesRoseburia_inulinivorans-0.0580.01170.018
genusDialister0.0580.01230.0189
classBacilli-0.0580.01270.0195
speciesLactobacillus_ruminis0.0570.01370.0209
orderLactobacillales-0.0570.01390.0212
speciesLactococcus_garvieae-0.0560.01450.022
speciesLactobacillus_fermentum-0.0560.01470.0222
speciesOscillibacter_sp_KLE_17450.0560.0160.0241
genusButyricicoccus0.0550.01690.0253
speciesButyricicoccus_pullicaecorum0.0550.01690.0253
speciesKlebsiella_sp_MS_92_3-0.0550.01750.0261
speciesLachnospiraceae_bacterium_5_1_57FAA-0.0550.01820.0271
speciesStreptococcus_vestibularis-0.0550.01830.0272
genusMyoviridae_noname-0.0540.01870.0276
speciesBifidobacterium_angulatum0.0540.01870.0276
speciesBacteroides_sp_3_1_19-0.0540.02060.0303
familyLeuconostocaceae-0.0530.02210.0324
genusTunalikevirus-0.0520.02320.0339
genusPyramidobacter-0.0520.02350.0341
speciesPyramidobacter_piscolens-0.0520.02350.0341
speciesParabacteroides_unclassified-0.0520.02430.0352
speciesLactobacillus_delbrueckii0.0520.02450.0354
speciesCoprobacillus_sp_D60.0520.02510.0361
speciesCoprobacillus_sp_29_10.0520.02570.0368
speciesParaprevotella_xylaniphila0.0520.02570.0368
familyLactobacillaceae-0.0510.02710.0386
familyClostridiales_noname0.0510.02830.0402
speciesKlebsiella_phage_KP36-0.050.02990.0424
speciesBacteroides_vulgatus-0.050.03180.0449
orderViruses_noname0.0490.03390.0478
genusLactobacillus-0.0480.03690.0518
speciesLactobacillus_crispatus-0.0480.03850.0539
speciesRothia_mucilaginosa-0.0480.03950.0552
speciesAcidaminococcus_intestini-0.0470.04030.0561
genusCampylobacter-0.0470.04160.0578
speciesLachnospiraceae_bacterium_5_1_63FAA0.0460.04560.0631
genusProteus-0.0460.04580.0632
speciesEubacterium_dolichum-0.0460.04880.067
speciesAcidaminococcus_unclassified0.0460.04880.067
speciesDialister_invisus0.0450.05320.0728
genusLachnospiraceae_noname0.0440.05830.0794
genusClostridiales_noname-0.0440.05840.0794
genusSolobacterium-0.0430.06070.0821
speciesSolobacterium_moorei-0.0430.06070.0821
speciesHoldemania_sp_AP2-0.0430.06180.0833
speciesLactobacillus_vaginalis-0.0430.0620.0834
familyCampylobacteraceae-0.0430.06530.0876
genusBilophila0.0420.06770.0905
speciesBifidobacterium_dentium-0.0420.06890.0919
speciesErysipelotrichaceae_bacterium_3_1_53-0.0410.07330.0975
speciesParabacteroides_sp_20_30.0410.0740.0981
speciesParaprevotella_clara0.0410.07570.1
speciesAnaerotruncus_colihominis0.040.0810.107
familyMicrococcaceae-0.040.08390.11
genusRothia-0.040.08560.112
speciesBilophila_unclassified0.0390.08880.116
classEpsilonproteobacteria-0.0380.09640.125
orderCampylobacterales-0.0380.09640.125
familyActinomycetaceae0.0380.09750.126
speciesCollinsella_intestinalis-0.0360.1240.16
genusParabacteroides0.0350.1250.161
speciesLactococcus_phage_jm20.0350.1250.161
speciesBacteroides_dorei0.0350.1260.162
speciesParaprevotella_unclassified0.0350.1270.162
speciesBacteroides_clarus0.0350.130.166
genusActinomyces0.0350.1340.17
speciesKlebsiella_oxytoca-0.0350.1350.171
genusMorganella-0.0350.1360.172
speciesMorganella_morganii-0.0350.1360.172
speciesLactobacillus_gasseri-0.0340.1370.172
genusPeptoniphilus0.0340.1440.18
speciesEggerthella_sp_1_3_56FAA-0.0340.1440.18
speciesStreptococcus_lutetiensis-0.0330.150.187
familyClostridiales_Family_XI_Incertae_Sedis0.0330.1510.188
genusButyricimonas0.0330.1580.195
speciesProteus_mirabilis-0.0330.1580.195
speciesButyricimonas_synergistica0.0330.1580.195
genusParaprevotella0.0330.1590.196
speciesMegasphaera_elsdenii-0.0320.1630.2
speciesClostridium_bartlettii-0.0320.1670.205
genusSlackia0.0320.1710.209
speciesLactobacillus_amylovorus-0.0310.1780.217
speciesParabacteroides_distasonis-0.0310.1870.227
orderActinomycetales0.030.1970.239
speciesBacteroides_eggerthii0.0290.2030.246
speciesBacteroides_sp_1_1_60.0290.2040.246
phylumSynergistetes-0.0280.2220.265
classSynergistia-0.0280.2220.265
orderSynergistales-0.0280.2220.265
familySynergistaceae-0.0280.2220.265
speciesEnterococcus_faecium0.0280.2250.268
speciesLactococcus_phage_936_sensu_lato0.0280.2330.277
speciesLactobacillus_rhamnosus0.0270.2350.278
speciesBacteroides_salyersiae-0.0270.2350.278
orderPseudomonadales0.0260.2530.298
speciesCollinsella_unclassified0.0260.2530.298
speciesLactobacillus_oris-0.0260.2640.31
speciesBacteroides_barnesiae0.0260.2690.315
speciesBacteroides_intestinalis-0.0250.2710.317
genusParvimonas0.0250.2750.32
speciesParvimonas_unclassified0.0250.2760.321
speciesGemella_morbillorum-0.0240.290.336
speciesBacteroides_coprophilus0.0240.2960.342
speciesEnterobacteria_phage_HK544-0.0240.2980.344
speciesBacteroides_caccae0.0240.310.357
genusParasutterella-0.0230.3130.359
speciesParasutterella_excrementihominis-0.0230.3130.359
speciesParabacteroides_johnsonii0.0220.3390.387
speciesBacteroides_fluxus-0.0220.340.388
speciesEggerthella_lenta-0.0210.3570.406
speciesSlackia_piriformis0.020.3770.428
genusBurkholderiales_noname-0.0190.4010.453
speciesBurkholderiales_bacterium_1_1_47-0.0190.4010.453
orderAeromonadales-0.0190.4070.458
speciesLachnospiraceae_bacterium_1_1_57FAA0.0190.4080.459
familyBurkholderiales_noname-0.0190.4210.472
speciesMitsuokella_multacida-0.0180.4350.487
speciesBacteroides_sp_2_1_22-0.0180.4410.492
speciesLactobacillus_reuteri-0.0170.4690.522
genusClostridiaceae_noname0.0170.4750.526
speciesClostridiaceae_bacterium_JC1180.0170.4750.526
genusLambdalikevirus0.0160.4770.527
speciesStreptococcus_mutans-0.0160.480.529
speciesDialister_succinatiphilus0.0150.510.561
speciesBacteroides_faecis0.0150.5150.564
speciesLachnospiraceae_bacterium_8_1_57FAA-0.0150.5150.564
genusFaecalibacterium0.0150.5180.564
speciesFaecalibacterium_prausnitzii0.0150.5180.564
speciesStreptococcus_phage_Sfi210.0150.5190.564
speciesClostridium_hathewayi-0.0150.5280.573
genusLeuconostoc0.0150.5290.573
speciesEnterococcus_faecalis-0.0140.5480.592
speciesPrevotella_bivia-0.0130.5680.612
genusClostridium0.0120.6040.649
familyClostridiaceae0.0120.6150.66
genusAcidaminococcus0.0120.6170.66
speciesLactobacillus_plantarum-0.0120.6180.66
genusPeptostreptococcaceae_noname-0.0110.6240.665
speciesOscillibacter_sp_KLE_1728-0.0090.6860.729
speciesAcidaminococcus_fermentans0.0090.7070.75
genusStaphylococcus-0.0080.7190.761
genusPeptostreptococcus-0.0080.7430.783
speciesRoseburia_intestinalis0.0080.7430.783
speciesRuminococcus_sp_JC3040.0060.8010.842
familyEnterococcaceae0.0060.8090.849
genusSutterellaceae_unclassified-0.0050.8170.855
genusSuccinatimonas0.0050.8210.855
speciesSuccinatimonas_hippei0.0050.8210.855
speciesClostridium_asparagiforme0.0050.8230.856
genusEnterococcus0.0050.8260.857
familyPodoviridae0.0050.8410.871
speciesErysipelotrichaceae_bacterium_5_2_54FAA-0.0040.8580.886
speciesPeptostreptococcus_stomatis0.0040.860.886
speciesStreptococcus_parasanguinis-0.0030.8870.912
speciesEscherichia_unclassified0.0030.8910.914
familySuccinivibrionaceae0.0030.9060.926
familyPeptostreptococcaceae0.0030.9060.926
speciesCollinsella_tanakaei0.0020.9290.945
speciesEubacterium_sp_3_1_310.0020.9290.945
speciesDorea_unclassified-0.0010.9490.963
familyStaphylococcaceae-0.0010.9510.963
speciesBacteroides_sp_4_3_47FAA0.0010.9620.972
speciesLactobacillus_acidophilus0.0010.9640.972
speciesLactococcus_phage_bIL670.0010.9720.978
speciesClostridium_sp_KLE_17550.0010.9820.986
familyViruses_noname0.00.990.99
genusViruses_noname0.00.990.99
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Association of query gene abundance with clinical phenotypes:

Boxplots:


Statistics:

pheno country case_n ctrl_n case_mean ctrl_mean pvalue rank percentile
Crohns diseaseSpain17662.23955618804e-050.0002386224618760.00124391294938443614.7498
Liver cirrhosisChina1201148.95554140855e-069.84410064343e-060.1229547097121733858.2418
Rheumatoid arthritisChina127980.0001817139252697.38598885038e-050.13135062289662922.1062
Type II diabetesSweden53920.0007437340401330.0007053756524040.216655158732766225.9465
Ulcerative colitisSpain78660.0002989418105860.0002386224618760.2638597788431270841.9212
Colorectal cancerAustria64350.0006351054596890.0008529402733980.3024609475731251042.3264
Type II diabetesDenmark752770.0007191904267940.0002481912698980.3268729100261643753.8794
Type II diabetesChina1831853.50316644711e-052.74578660655e-050.8766732486672796592.4188
ObesityDenmark1691230.0001882416404930.0003319320225620.978662561053001998.711
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Citation:

Nayfach S, Fischbach MA, Pollard KS. MetaQuery: a web server for rapid annotation and quantitative analysis of specific genes in the human gut microbiome. Bioinformatics 2015;31(14). doi:10.1093/bioinformatics/btv382