MetaQuery: quantitative analysis of the human gut microbiome

Results

Estimated gene abundances and results from statistical analyses

Job details:

Submission date: 2020-01-09 18:27:22 PST
Job id & description: 1636, PPY8637
Query type: protein
Count queries & homologs: 17, 65
Min % identity & max e-value: 70%, 1e-5
Min % query & target coverage: 70%, 70%

Click here to download results

Table of contents:


Gut microbiome genes homologous to your query gene:

query_id target_id status kegg eggnog phylum genus query_cov target_cov percent_identity
locus_tag="XBW1359996CompleteK06200COG1966ProteobacteriaEscherichia100.0100.090.93
locus_tag="XBW1358757CompleteK06200COG1966ProteobacteriaProvidencia100.0100.089.68
locus_tag="XBW1359163CompleteK06200COG1966ProteobacteriaKlebsiella100.0100.088.15
locus_tag="XBW1360317CompleteK06200COG1966ProteobacteriaKlebsiella100.0100.088.01
locus_tag="XBW1359517CompleteK06200COG1966ProteobacteriaKlebsiella100.0100.087.87
locus_tag="XBW1359071CompleteK06200COG1966ProteobacteriaEnterobacter100.0100.087.45
locus_tag="XBW1360456CompleteK06200COG1966ProteobacteriaCitrobacter100.0100.087.87
locus_tag="XBW1343672Lack 5'-endK06200COG1966ProteobacteriaEscherichia100.098.3587.31
locus_tag="XBW1360253Lack 3'-endK06200COG1966ProteobacteriaEnterobacter100.0100.087.03
locus_tag="XBW1358897CompleteK06200COG1966ProteobacteriaEnterobacter100.0100.087.03
locus_tag="XBW1358809CompleteK06200COG1966ProteobacteriaEnterobacter100.0100.087.03
locus_tag="XBW1359091CompleteK06200COG1966ProteobacteriaEnterobacter100.0100.086.61
locus_tag="XBW1359997CompleteK06200COG1966ProteobacteriaProteus100.0100.087.03
locus_tag="XBW1360426CompleteK06200COG1966ProteobacteriaCitrobacter100.0100.087.45
locus_tag="XBW11285315CompleteK03837COG0814ProteobacteriaProteus100.0100.084.88
locus_tag="XBW11301993CompleteK03837COG0814Proteobacteriaunknown100.0100.083.9
locus_tag="XBW11286715CompleteK03837COG0814ProteobacteriaEnterobacter100.0100.083.11
locus_tag="XBW11158417CompleteK03837COG0814ProteobacteriaCitrobacter100.096.183.56
locus_tag="XBW11286366CompleteK03837COG0814ProteobacteriaEnterobacter100.0100.083.11
locus_tag="XBW11287972CompleteK03837COG0814ProteobacteriaEnterobacter100.0100.082.88
locus_tag="XBW11099725CompleteK03837COG0814ProteobacteriaCitrobacter100.094.2683.33
locus_tag="XBW11053226CompleteK03837COG0814ProteobacteriaEnterobacter100.092.6883.11
locus_tag="XBW11284203CompleteK03837COG0814ProteobacteriaCitrobacter100.0100.082.88
locus_tag="XBW11255081Lack 5'-endK03837COG0814ProteobacteriaEscherichia100.099.1181.53
locus_tag="XBW11452553CompleteK03837COG0814ProteobacteriaEnterobacter95.01100.084.6
locus_tag="XBW11336849CompleteK03837COG0814Proteobacteriaunknown97.0598.1782.24
locus_tag="XBW11249398CompleteK03327COG0534ProteobacteriaProvidencia100.099.5578.48
locus_tag="XBW11263422CompleteK03327COG0534ProteobacteriaProteus100.0100.077.35
locus_tag="XBW11422299CompleteK03837COG0814ProteobacteriaEscherichia100.0100.077.7
locus_tag="XBW11248667CompleteK03327COG0534unknownunknown100.099.5573.99
locus_tag="XBW11363900CompleteK03837COG0814unknownunknown96.1598.1570.52
locus_tag="XBW11345464CompleteK03837COG0814unknownunknown95.6997.9375.35
locus_tag="XBW11345381CompleteK03837COG0814unknownunknown95.6997.9375.12
locus_tag="XBW11266435CompleteK03837COG0814FirmicutesMegasphaera95.9295.0672.58
locus_tag="XBW11266857CompleteK03837COG0814FirmicutesMegasphaera95.9295.0672.34
locus_tag="XBW11267513CompleteK03837COG0814Firmicutesunknown95.9295.0672.58
locus_tag="XBW12247931CompleteK03837COG0814ProteobacteriaEnterobacter75.7498.5482.49
locus_tag="XBW12634521Lack 5'-endK03837COG0814ProteobacteriaCitrobacter70.07100.081.41
locus_tag="XBW12118137CompleteK02234COG0523unknownunknown100.089.872.87
locus_tag="XBW12462580CompleteK02234COG0523ProteobacteriaProteus100.097.5472.56
locus_tag="XBW12503139CompleteK02234COG0523ProteobacteriaProvidencia100.098.4575.08
locus_tag="XBW12552925CompleteK02234COG0523ProteobacteriaCitrobacter100.099.3770.66
locus_tag="XBW12560186CompleteK02234COG0523ProteobacteriaCitrobacter100.099.3770.66
locus_tag="XBW12400044CompleteK02234COG0523ProteobacteriaEnterobacter100.095.4570.66
locus_tag="XBW12201362CompleteK02234COG0523ProteobacteriaEscherichia100.091.3370.98
locus_tag="XBW12572134CompleteK02234COG0523ProteobacteriaEnterobacter100.099.3770.98
locus_tag="XBW12403426CompleteK02234COG0523ProteobacteriaEnterobacter100.095.4570.03
locus_tag="XBW12571994CompleteK02234COG0523ProteobacteriaEnterobacter100.099.3770.98
locus_tag="XBW14211182CompleteunknownCOG1462Proteobacteriaunknown99.198.6576.92
locus_tag="XBW14183651CompleteunknownCOG1462Proteobacteriaunknown98.2197.7774.89
locus_tag="XBW14195181CompleteunknownCOG1462unknownunknown97.7698.2173.97
locus_tag="XBW14211371CompleteunknownCOG1462ProteobacteriaAggregatibacter100.0100.071.3
locus_tag="XBW13910642CompleteunknownCOG1462ProteobacteriaProteus98.2192.4171.69
locus_tag="XBW14609173CompleteK07357COG0582ProteobacteriaProteus100.089.2777.05
locus_tag="XBW15072826CompleteK07357COG0582unknownunknown100.097.8672.13
locus_tag="XBW15679736Lack 3'-endunknownCOG1462ProteobacteriaProteus73.9998.2170.3
locus_tag="XBW18607653CompleteunknownCOG2879ProteobacteriaProvidencia100.0100.082.09
locus_tag="XBW18589918CompleteunknownCOG2879ProteobacteriaKlebsiella100.0100.079.1
locus_tag="XBW18590785CompleteunknownCOG2879ProteobacteriaKlebsiella100.0100.077.61
locus_tag="XBW17905522Lack 5'-endunknownCOG2879ProteobacteriaEnterobacter100.077.0177.61
locus_tag="XBW17942098CompleteunknownCOG2879ProteobacteriaEnterobacter100.077.9177.61
locus_tag="XBW18701611CompleteunknownCOG2879ProteobacteriaCitrobacter100.0100.073.13
locus_tag="XBW18566317CompleteunknownCOG2879ProteobacteriaProteus100.0100.082.35
locus_tag="XBW18672857CompleteunknownCOG2879ProteobacteriaCitrobacter100.0100.070.15
locus_tag="XBW18662025CompleteunknownCOG2879ProteobacteriaCitrobacter100.0100.070.15
Click on arrows to sort table data. Shift+click to sort by multiple columns.

The abundance of your query across gut microbiome samples:




The prevalence of your query across gut microbiome samples:




Taxonomic groups correlated with your query gene:

tax_level tax_name spearman_rho pvalue qvalue
classGammaproteobacteria0.9060.00.0
orderEnterobacteriales0.9570.00.0
familyEnterobacteriaceae0.9570.00.0
genusEscherichia0.9090.00.0
speciesEscherichia_coli0.8850.00.0
phylumProteobacteria0.7023.37e-2772.65e-275
speciesEscherichia_unclassified0.5782.26e-1671.52e-165
genusKlebsiella0.5711.41e-1628.32e-161
speciesKlebsiella_pneumoniae0.543.87e-1422.03e-140
genusPantoea0.4553.56e-961.53e-94
speciesPantoea_unclassified0.4553.56e-961.53e-94
genusEnterobacter0.4233.1e-821.22e-80
speciesEnterobacter_cloacae0.4221.28e-814.65e-80
genusCitrobacter0.3589.92e-583.34e-56
speciesRuminococcus_gnavus0.3551.08e-563.4e-55
speciesCitrobacter_unclassified0.3474.44e-541.31e-52
speciesCitrobacter_freundii0.3439.26e-532.57e-51
familyFusobacteriaceae0.3383.6e-519.44e-50
genusFusobacterium0.3322.41e-495.99e-48
phylumFusobacteria0.3315.04e-491.08e-47
classFusobacteriia0.3315.04e-491.08e-47
orderFusobacteriales0.3315.04e-491.08e-47
speciesClostridium_nexile0.3253.81e-477.82e-46
speciesSubdoligranulum_unclassified-0.3051.15e-412.26e-40
speciesLachnospiraceae_bacterium_7_1_58FAA-0.3021.09e-402.06e-39
genusSubdoligranulum-0.2997.49e-401.36e-38
genusCoprobacillus0.291.56e-372.73e-36
speciesKlebsiella_oxytoca0.2852.81e-364.74e-35
speciesEubacterium_siraeum-0.2844.74e-367.71e-35
genusMegasphaera0.2837.81e-361.23e-34
speciesClostridium_bolteae0.2741.37e-332.09e-32
speciesCoprobacillus_unclassified0.2732.83e-334.17e-32
genusButyrivibrio-0.2692.55e-323.65e-31
speciesAnaerotruncus_unclassified-0.2669.65e-321.34e-30
speciesClostridium_hathewayi0.2611.33e-301.79e-29
speciesClostridium_ramosum0.263.3e-304.33e-29
speciesKlebsiella_unclassified0.255.21e-286.65e-27
genusWeissella0.2498.95e-281.11e-26
speciesEubacterium_ramulus-0.2441.16e-261.4e-25
genusCoprococcus-0.2399.34e-261.1e-24
genusPseudoflavonifractor-0.2381.4e-251.57e-24
speciesPseudoflavonifractor_capillosus-0.2381.4e-251.57e-24
genusEnterococcus0.2372.44e-252.68e-24
familyEnterococcaceae0.2365.24e-255.62e-24
genusBarnesiella-0.2315.22e-245.36e-23
speciesBarnesiella_intestinihominis-0.2315.22e-245.36e-23
speciesWeissella_confusa0.237.13e-247.16e-23
speciesFusobacterium_ulcerans0.2291.33e-231.31e-22
speciesEubacterium_rectale-0.2255.72e-235.51e-22
speciesClostridium_symbiosum0.2231.38e-221.3e-21
speciesClostridium_perfringens0.2232.04e-221.89e-21
familyRuminococcaceae-0.2213.65e-223.31e-21
genusEubacterium-0.2214.08e-223.63e-21
familyEubacteriaceae-0.2214.21e-223.68e-21
speciesSutterella_wadsworthensis-0.2214.96e-224.26e-21
speciesBifidobacterium_adolescentis-0.227.52e-226.34e-21
speciesBacteroides_uniformis-0.2191.12e-219.27e-21
familyClostridiaceae0.2171.94e-211.58e-20
genusClostridium0.2154.65e-213.72e-20
speciesLactobacillus_salivarius0.2148.91e-217.01e-20
classClostridia-0.2149.27e-217.06e-20
orderClostridiales-0.2149.27e-217.06e-20
speciesStreptococcus_anginosus0.2131.28e-209.59e-20
familyBacteroidales_noname-0.2113.52e-202.52e-19
genusBacteroidales_noname-0.2113.52e-202.52e-19
speciesBacteroidales_bacterium_ph8-0.2113.52e-202.52e-19
speciesButyrivibrio_unclassified-0.214.96e-203.48e-19
speciesCoprococcus_comes-0.215.01e-203.48e-19
genusSutterella-0.2095.55e-203.8e-19
speciesClostridium_leptum-0.2089.84e-206.63e-19
speciesVeillonella_parvula0.2071.29e-198.58e-19
speciesMegasphaera_micronuciformis0.2071.56e-191.02e-18
familyLeuconostocaceae0.2053.77e-192.44e-18
speciesLachnospiraceae_bacterium_3_1_46FAA-0.2054.14e-192.64e-18
speciesFusobacterium_nucleatum0.2044.88e-193.07e-18
genusCoprobacter-0.2046.01e-193.68e-18
speciesCoprobacter_fastidiosus-0.2046.01e-193.68e-18
speciesEggerthella_unclassified0.2046.17e-193.73e-18
orderLactobacillales0.2029.73e-195.81e-18
speciesBacteroides_fragilis0.2021.03e-186.08e-18
classBacilli0.2021.35e-187.87e-18
speciesLactococcus_garvieae0.1993.09e-181.77e-17
speciesMegamonas_unclassified0.1993.11e-181.77e-17
genusMegamonas0.1993.66e-182.06e-17
speciesMegasphaera_unclassified0.1994.2e-182.33e-17
speciesFusobacterium_varium0.1961.12e-176.15e-17
genusVeillonella0.1951.6e-178.68e-17
genusEggerthella0.1951.98e-171.06e-16
familyRikenellaceae-0.1942.27e-171.19e-16
genusAlistipes-0.1942.27e-171.19e-16
speciesClostridiales_bacterium_1_7_47FAA0.1934.39e-172.28e-16
speciesEnterococcus_faecalis0.1925.16e-172.65e-16
speciesStreptococcus_infantarius0.1916.68e-173.39e-16
speciesLactobacillus_mucosae0.1918.24e-174.14e-16
speciesRoseburia_hominis-0.191.24e-166.16e-16
speciesWeissella_cibaria0.1891.47e-167.23e-16
speciesC2likevirus_unclassified-0.1891.51e-167.35e-16
speciesFusobacterium_mortiferum0.1891.56e-167.51e-16
genusRuminococcaceae_noname-0.1882.38e-161.12e-15
speciesRuminococcaceae_bacterium_D16-0.1882.38e-161.12e-15
speciesDorea_longicatena-0.1873.95e-161.85e-15
genusC2likevirus-0.1864.47e-162.07e-15
speciesMitsuokella_unclassified-0.1864.9e-162.25e-15
speciesEubacterium_hallii-0.1865.84e-162.65e-15
speciesOscillibacter_unclassified-0.1841.16e-155.21e-15
speciesAnaerostipes_hadrus-0.1822.37e-151.06e-14
speciesAlistipes_shahii-0.1813.16e-151.39e-14
speciesCoprococcus_catus-0.184.85e-152.12e-14
speciesLachnospiraceae_bacterium_9_1_43BFAA0.184.93e-152.13e-14
genusDorea-0.184.97e-152.13e-14
speciesAlistipes_senegalensis-0.185.03e-152.13e-14
familyOscillospiraceae-0.185.09e-152.13e-14
genusOscillibacter-0.185.09e-152.13e-14
speciesClostridium_citroniae0.1795.9e-152.44e-14
speciesStreptococcus_thermophilus-0.1797.29e-152.99e-14
genusOdoribacter-0.1771.12e-144.56e-14
genusAnaerotruncus-0.1771.24e-145e-14
genusMitsuokella-0.1752.3e-149.16e-14
speciesEnterobacter_aerogenes0.1752.31e-149.16e-14
speciesLachnospiraceae_bacterium_8_1_57FAA-0.1735.24e-142.06e-13
genusFlavonifractor0.1727.77e-143.01e-13
speciesFlavonifractor_plautii0.1727.77e-143.01e-13
genusPyramidobacter0.1719.76e-143.67e-13
speciesPyramidobacter_piscolens0.1719.76e-143.67e-13
phylumVerrucomicrobia-0.1711.01e-133.67e-13
classVerrucomicrobiae-0.1711.01e-133.67e-13
orderVerrucomicrobiales-0.1711.01e-133.67e-13
familyVerrucomicrobiaceae-0.1711.01e-133.67e-13
genusAkkermansia-0.1711.01e-133.67e-13
speciesAkkermansia_muciniphila-0.1711.01e-133.67e-13
phylumSynergistetes0.1711.05e-133.7e-13
classSynergistia0.1711.05e-133.7e-13
orderSynergistales0.1711.05e-133.7e-13
familySynergistaceae0.1711.05e-133.7e-13
speciesOdoribacter_splanchnicus-0.1682.41e-138.43e-13
familyLactobacillaceae0.1682.55e-138.85e-13
speciesMegasphaera_elsdenii0.1673.13e-131.08e-12
speciesAlistipes_putredinis-0.1674.16e-131.42e-12
genusLactobacillus0.1674.24e-131.44e-12
speciesBifidobacterium_dentium0.1621.67e-125.63e-12
familyBacillales_noname0.1621.72e-125.72e-12
genusGemella0.1621.72e-125.72e-12
speciesEnterococcus_faecium0.1586.63e-122.19e-11
speciesVeillonella_unclassified0.1578.19e-122.68e-11
genusPrevotella0.1579.45e-123.08e-11
speciesVeillonella_dispar0.1579.73e-123.15e-11
speciesBacteroides_plebeius0.1542.1e-116.74e-11
speciesStreptococcus_salivarius0.1532.97e-119.47e-11
speciesCollinsella_aerofaciens-0.1523.78e-111.2e-10
phylumFirmicutes-0.1524.07e-111.28e-10
speciesPrevotella_buccae0.1515.71e-111.78e-10
speciesButyrivibrio_crossotus-0.1515.97e-111.85e-10
familyPorphyromonadaceae-0.157.32e-112.26e-10
speciesStreptococcus_mitis_oralis_pneumoniae0.157.61e-112.33e-10
speciesDorea_formicigenerans-0.1498.44e-112.57e-10
genusMorganella0.1499e-112.71e-10
speciesMorganella_morganii0.1499e-112.71e-10
familySutterellaceae-0.1491.02e-103.05e-10
genusSolobacterium0.1471.61e-104.75e-10
speciesSolobacterium_moorei0.1471.61e-104.75e-10
speciesAnaerostipes_unclassified0.1471.71e-105.01e-10
speciesLachnospiraceae_bacterium_6_1_63FAA0.1434.94e-101.44e-09
genusCollinsella-0.1435.36e-101.55e-09
speciesCoprococcus_sp_ART55_1-0.1435.56e-101.6e-09
orderBurkholderiales-0.1426.23e-101.78e-09
speciesBifidobacterium_pseudocatenulatum0.1426.31e-101.79e-09
speciesBacteroides_stercoris0.1427.15e-102.02e-09
speciesRuminococcus_lactaris-0.1427.21e-102.03e-09
speciesStreptococcus_lutetiensis0.141.19e-093.32e-09
speciesKlebsiella_sp_MS_92_30.141.24e-093.44e-09
speciesRuminococcus_sp_5_1_39BFAA-0.141.29e-093.56e-09
speciesMegamonas_rupellensis0.1391.42e-093.9e-09
familyStreptococcaceae0.1391.66e-094.53e-09
speciesPrevotella_copri0.1382e-095.43e-09
classBetaproteobacteria-0.1382.23e-096.01e-09
genusBlautia0.1382.27e-096.09e-09
speciesAlistipes_onderdonkii-0.1372.53e-096.75e-09
genusProteus0.1372.63e-096.97e-09
genusClostridiales_noname0.1372.92e-097.7e-09
orderBacillales0.1354.96e-091.3e-08
speciesMegamonas_hypermegale0.1345.56e-091.45e-08
familyPeptostreptococcaceae0.1345.73e-091.47e-08
classEpsilonproteobacteria0.1345.75e-091.47e-08
orderCampylobacterales0.1345.75e-091.47e-08
genusCampylobacter0.1345.89e-091.5e-08
speciesMethanobrevibacter_smithii-0.1346.51e-091.65e-08
speciesLactobacillus_fermentum0.1337.63e-091.93e-08
familyCampylobacteraceae0.1337.99e-092.01e-08
genusPeptostreptococcus0.1321.06e-082.65e-08
genusStreptococcus0.1311.23e-083.06e-08
genusMethanobrevibacter-0.1311.37e-083.39e-08
speciesAcidaminococcus_intestini0.1291.97e-084.84e-08
phylumEuryarchaeota-0.1292.07e-085.04e-08
speciesBlautia_hydrogenotrophica-0.1292.07e-085.04e-08
speciesLactobacillus_sanfranciscensis0.1282.54e-086.15e-08
speciesClostridium_clostridioforme0.1282.7e-086.5e-08
genusFaecalibacterium-0.1282.82e-086.72e-08
speciesFaecalibacterium_prausnitzii-0.1282.82e-086.72e-08
speciesVeillonella_atypica0.1273.47e-088.23e-08
classMethanobacteria-0.1273.88e-089.07e-08
orderMethanobacteriales-0.1273.88e-089.07e-08
familyMethanobacteriaceae-0.1273.88e-089.07e-08
familyVeillonellaceae0.1264.24e-089.86e-08
speciesProteus_mirabilis0.1264.77e-081.1e-07
speciesLachnospiraceae_bacterium_2_1_46FAA0.1265.12e-081.18e-07
speciesEubacterium_ventriosum-0.1255.71e-081.31e-07
speciesPrevotella_stercorea0.1256.44e-081.47e-07
speciesLachnospiraceae_bacterium_2_1_58FAA0.1256.56e-081.49e-07
familySiphoviridae-0.1247.93e-081.79e-07
speciesParaprevotella_xylaniphila-0.1231e-072.25e-07
speciesHaemophilus_parainfluenzae0.1221.1e-072.46e-07
orderPasteurellales0.1221.33e-072.95e-07
familyPasteurellaceae0.1221.33e-072.95e-07
genusHaemophilus0.1211.58e-073.48e-07
familyMyoviridae0.121.78e-073.91e-07
speciesLeuconostoc_lactis0.122.05e-074.48e-07
speciesStreptococcus_australis0.1192.41e-075.24e-07
genusAggregatibacter0.1192.75e-075.95e-07
genusPeptostreptococcaceae_noname0.1183.45e-077.44e-07
speciesStreptococcus_gordonii0.1173.5e-077.51e-07
speciesClostridium_bartlettii0.1165.35e-071.14e-06
speciesBacteroides_intestinalis0.1148.49e-071.81e-06
speciesAcidaminococcus_fermentans0.1148.61e-071.82e-06
speciesEnterobacteria_phage_HK5440.1139.95e-072.1e-06
speciesPeptostreptococcus_stomatis0.1121.28e-062.69e-06
speciesStreptococcus_pasteurianus0.1121.33e-062.77e-06
speciesAlistipes_indistinctus-0.1121.33e-062.77e-06
genusRuminococcus-0.1111.45e-063e-06
familyPropionibacteriaceae-0.1111.53e-063.15e-06
speciesAggregatibacter_segnis0.1111.64e-063.37e-06
speciesParaprevotella_unclassified-0.1092.07e-064.23e-06
speciesGemella_morbillorum0.1092.39e-064.86e-06
familyActinomycetaceae0.1092.48e-065.02e-06
genusParaprevotella-0.1092.49e-065.02e-06
speciesOdoribacter_unclassified-0.1083.05e-066.13e-06
genusAdlercreutzia-0.1073.77e-067.51e-06
speciesAdlercreutzia_equolifaciens-0.1073.77e-067.51e-06
speciesMegamonas_funiformis0.1064.76e-069.44e-06
familyClostridiales_Family_XI_Incertae_Sedis0.1055.36e-061.06e-05
genusAnaerostipes-0.1055.83e-061.15e-05
speciesCoprococcus_eutactus-0.1045.99e-061.17e-05
genusActinomyces0.1046.35e-061.24e-05
speciesParaprevotella_clara-0.1046.91e-061.34e-05
genusAcidaminococcaceae_unclassified-0.1037.55e-061.46e-05
speciesLachnospiraceae_bacterium_5_1_63FAA-0.1037.71e-061.49e-05
speciesRoseburia_intestinalis-0.1037.79e-061.49e-05
speciesAlistipes_sp_HGB5-0.1038.16e-061.56e-05
speciesEubacterium_eligens-0.1029.32e-061.77e-05
speciesRuminococcus_obeum-0.1029.47e-061.8e-05
speciesBifidobacterium_catenulatum-0.1021.01e-051.91e-05
speciesAlistipes_finegoldii-0.1011.14e-052.14e-05
speciesBacteroides_coprocola0.1011.17e-052.19e-05
speciesStreptococcus_vestibularis0.1011.23e-052.29e-05
speciesBacteroides_sp_3_1_190.1011.27e-052.36e-05
familyClostridiales_noname0.0991.74e-053.22e-05
speciesRuminococcus_champanellensis-0.0982.33e-054.3e-05
familyLachnospiraceae-0.0972.43e-054.46e-05
speciesCampylobacter_concisus0.0972.63e-054.81e-05
speciesParabacteroides_merdae-0.0972.83e-055.16e-05
speciesBacteroides_thetaiotaomicron0.0963.37e-056.12e-05
speciesRothia_mucilaginosa0.0944.42e-057.99e-05
genusLambdalikevirus0.0944.68e-058.43e-05
speciesLactobacillus_amylovorus0.0945.03e-059.03e-05
speciesLactobacillus_crispatus0.0926.3e-050.000113
speciesLachnospiraceae_bacterium_1_4_56FAA0.0926.6e-050.000118
speciesRoseburia_unclassified-0.090.0001030.000183
speciesClostridium_sp_L2_50-0.0880.0001330.000235
speciesBacteroides_salyersiae0.0880.0001340.000236
speciesBacteroides_nordii0.0880.0001490.000261
genusRoseburia-0.0870.0001620.000283
speciesPorphyromonas_uenonis0.0860.00020.000348
speciesLachnospiraceae_bacterium_5_1_57FAA0.0860.0002130.00037
speciesErysipelotrichaceae_bacterium_21_3-0.0850.0002150.000372
speciesEubacterium_limosum0.0850.0002370.000408
speciesEggerthella_lenta0.0850.0002380.000408
speciesStreptococcus_sanguinis0.0850.0002450.000419
familyMicrococcaceae0.0840.0002770.000472
speciesBacteroides_dorei-0.0840.0002840.000482
genusRothia0.0840.0002940.000497
speciesLactobacillus_plantarum0.0840.0002980.000502
orderCoriobacteriales-0.0830.0003120.000522
familyCoriobacteriaceae-0.0830.0003120.000522
speciesHaemophilus_paraphrohaemolyticus0.0830.0003260.000544
speciesAlistipes_sp_AP11-0.0830.000350.000582
speciesClostridium_sp_ATCC_BAA_4420.0810.0004510.000747
speciesLactobacillus_vaginalis0.0810.000460.000759
speciesBlautia_producta0.080.0005040.000829
orderActinomycetales0.080.0005250.00086
speciesPropionibacterium_freudenreichii-0.080.0005410.000884
speciesLactobacillus_acidophilus-0.0790.0006360.00104
genusParabacteroides-0.0790.0006790.0011
genusCatenibacterium-0.0780.0006840.0011
speciesCatenibacterium_mitsuokai-0.0780.0006840.0011
speciesLactobacillus_oris0.0780.0007810.00125
classNegativicutes0.0770.0008770.0014
orderSelenomonadales0.0770.0008770.0014
speciesBacteroides_pectinophilus-0.0770.0008950.00142
genusPeptoniphilus0.0760.0009530.00151
speciesMethanobrevibacter_unclassified-0.0760.001010.00159
speciesOscillibacter_sp_KLE_1745-0.0760.001010.00159
genusActinobacillus0.0760.001080.00169
speciesActinobacillus_unclassified0.0760.001080.00169
speciesLactobacillus_gasseri0.0750.001140.00178
genusLeuconostoc0.0750.001180.00183
speciesBifidobacterium_breve0.0720.001790.00277
orderCaudovirales-0.0720.001850.00284
speciesDialister_invisus-0.0720.001850.00284
genusParvimonas0.0710.002080.00319
speciesParvimonas_unclassified0.0710.002110.00322
speciesCoprobacillus_sp_D60.0710.002230.0034
speciesStreptococcus_mutans0.0710.002280.00345
speciesLactococcus_phage_P680-0.0710.002280.00345
speciesClostridium_asparagiforme0.070.002430.00366
speciesBacteroides_oleiciplenus0.070.002630.00395
speciesOscillibacter_sp_KLE_1728-0.0690.002680.00402
speciesBacteroides_finegoldii0.0690.002970.00444
genusPorphyromonas0.0690.002980.00444
speciesCoprobacillus_sp_29_10.0680.003090.00459
speciesBifidobacterium_animalis-0.0670.003660.00542
genusDialister-0.0670.003870.00571
speciesOlsenella_unclassified-0.0670.003980.00585
genusSiphoviridae_noname-0.0660.004560.00668
genusPropionibacterium-0.0650.004940.00722
speciesParabacteroides_sp_D13-0.0650.005110.00744
speciesAlistipes_unclassified-0.0640.005450.00792
orderAeromonadales0.0640.005560.00805
speciesParabacteroides_goldsteinii0.0640.005750.0083
genusAcidaminococcus0.0630.006050.00871
genusMyoviridae_noname0.0630.006220.0089
speciesHoldemania_filiformis-0.0630.006220.0089
speciesEubacterium_biforme-0.0630.006380.0091
familyOxalobacteraceae-0.0620.006920.00984
genusOxalobacter-0.0610.008190.0116
speciesOxalobacter_formigenes-0.0610.008190.0116
speciesBilophila_unclassified0.0610.008440.0119
genusBilophila0.0610.008470.0119
speciesAcidaminococcus_unclassified-0.0610.008590.012
speciesCollinsella_tanakaei0.0610.008770.0122
speciesLactococcus_phage_936_sensu_lato-0.060.009160.0128
speciesHoldemania_unclassified-0.060.00930.0129
speciesBifidobacterium_angulatum-0.060.009730.0135
phylumViruses_noname-0.0590.0110.0151
classViruses_noname-0.0590.0110.0151
genusPhascolarctobacterium-0.0590.01130.0155
speciesPhascolarctobacterium_succinatutens-0.0590.01130.0155
classErysipelotrichia0.0580.0120.0163
orderErysipelotrichales0.0580.0120.0163
familyErysipelotrichaceae0.0580.0120.0163
speciesPrevotella_bivia0.0580.01210.0164
speciesBacteroides_xylanisolvens0.0580.01260.017
speciesBacteroides_sp_2_1_22-0.0570.01320.0177
speciesLachnospiraceae_bacterium_1_1_57FAA0.0570.01320.0177
speciesBacteroides_cellulosilyticus-0.0550.01680.0225
speciesBilophila_wadsworthia0.0550.01820.0243
classDeltaproteobacteria0.0540.01910.0253
orderDesulfovibrionales0.0540.01910.0253
familyDesulfovibrionaceae0.0540.01910.0253
speciesPorphyromonas_asaccharolytica0.0540.02050.027
speciesRuminococcus_bromii-0.0530.02130.028
speciesAnaerotruncus_colihominis0.0530.02280.0299
genusSutterellaceae_unclassified-0.0520.02360.0309
familyAcidaminococcaceae-0.0510.0280.0365
speciesDesulfovibrio_piger-0.0510.02830.0368
phylumBacteroidetes-0.050.0310.0401
classBacteroidia-0.050.03110.0401
orderBacteroidales-0.050.03110.0401
speciesHaemophilus_sputorum0.050.03230.0415
genusBifidobacterium-0.0490.03330.0427
genusTunalikevirus0.0480.03640.0466
speciesSutterella_parvirubra0.0480.03760.048
speciesHoldemania_sp_AP20.0480.03820.0486
speciesEubacterium_cylindroides-0.0470.04290.0544
speciesDesulfovibrio_desulfuricans-0.0460.04550.0576
orderBifidobacteriales-0.0460.0460.0579
familyBifidobacteriaceae-0.0460.0460.0579
speciesBacteroides_coprophilus0.0460.04890.0612
genusOlsenella-0.0460.0490.0612
speciesRoseburia_inulinivorans-0.0460.0490.0612
speciesLactococcus_phage_bIL67-0.0450.04980.062
speciesBifidobacterium_longum-0.0450.05250.0652
speciesBacteroides_sp_1_1_6-0.0450.05370.0665
speciesBacteroides_barnesiae-0.0440.05640.0697
speciesBacteroides_salanitronis-0.0440.05960.0734
speciesKlebsiella_phage_KP360.0410.07940.0976
phylumActinobacteria-0.0410.07990.0977
classActinobacteria-0.0410.07990.0977
genusHoldemania-0.0390.08870.108
speciesErysipelotrichaceae_bacterium_2_2_44A0.0390.09410.114
speciesLactococcus_phage_jm2-0.0380.0980.119
speciesLactobacillus_reuteri0.0370.1110.134
speciesPeptostreptococcus_anaerobius0.0370.1140.138
speciesLactococcus_lactis-0.0360.1180.142
speciesErysipelotrichaceae_bacterium_5_2_54FAA-0.0350.1310.157
familyPrevotellaceae0.0350.1320.158
speciesBacteroides_eggerthii0.0340.1410.168
speciesLactococcus_phage_phi7-0.0330.1540.184
speciesSubdoligranulum_sp_4_3_54A2FAA0.0330.1580.188
speciesClostridium_spiroforme-0.0320.1640.194
speciesClostridium_sp_KLE_1755-0.0320.1660.196
speciesDorea_unclassified-0.0320.1660.196
genusDesulfovibrio-0.0320.1720.202
speciesStreptococcus_parasanguinis0.0310.1760.207
speciesParabacteroides_unclassified0.0310.1840.216
genusGordonibacter-0.030.1880.219
speciesGordonibacter_pamelaeae-0.030.1880.219
speciesLactobacillus_rhamnosus0.030.2020.235
speciesBacteroides_vulgatus-0.0290.2120.246
genusErysipelotrichaceae_noname0.0280.2310.267
speciesBacteroides_ovatus-0.0270.2370.274
speciesCoriobacteriaceae_bacterium_phI-0.0270.2420.279
familyBacteroidaceae0.0270.250.286
genusBacteroides0.0270.250.286
speciesRuminococcus_sp_JC3040.0260.2560.293
orderViruses_noname-0.0260.2570.293
familyPodoviridae0.0260.2580.293
speciesLactobacillus_ruminis-0.0260.2610.296
orderPseudomonadales0.0260.2660.3
speciesPeptostreptococcaceae_noname_unclassified-0.0260.2660.3
speciesEubacterium_dolichum0.0260.270.304
speciesTuricibacter_unclassified-0.0240.290.326
genusCoriobacteriaceae_noname-0.0240.30.336
genusSlackia0.0240.3010.337
speciesBacteroides_massiliensis0.0240.3090.345
speciesParabacteroides_sp_20_3-0.0210.3720.414
genusTuricibacter-0.020.3920.435
genusLactococcus0.0190.4080.452
speciesParabacteroides_johnsonii0.0190.4130.457
genusMethanosphaera-0.0180.4390.483
speciesMethanosphaera_stadtmanae-0.0180.4390.483
speciesEubacterium_sp_3_1_31-0.0170.4740.52
speciesMitsuokella_multacida0.0170.4750.52
genusButyricimonas-0.0150.5130.559
speciesButyricimonas_synergistica-0.0150.5130.559
speciesErysipelotrichaceae_bacterium_6_1_450.0150.5140.559
genusLachnospiraceae_noname-0.0150.5220.566
genusStaphylococcus-0.0140.5310.575
genusSuccinatimonas0.0140.540.582
speciesSuccinatimonas_hippei0.0140.540.582
speciesLactobacillus_casei_paracasei-0.0140.5570.599
speciesCollinsella_unclassified-0.0130.5690.61
speciesLactobacillus_delbrueckii-0.0120.6040.646
speciesBacteroides_clarus0.0120.6050.646
speciesCollinsella_intestinalis0.0120.6090.649
speciesParabacteroides_distasonis-0.0110.6210.66
speciesSlackia_piriformis-0.0110.6340.672
speciesErysipelotrichaceae_bacterium_3_1_530.010.650.688
genusButyricicoccus0.010.6610.696
speciesButyricicoccus_pullicaecorum0.010.6610.696
speciesEggerthella_sp_1_3_56FAA-0.010.6770.712
speciesBacteroides_sp_4_3_47FAA0.0090.6840.717
speciesDialister_succinatiphilus0.0090.7040.737
familySuccinivibrionaceae0.0080.720.749
genusBurkholderiales_noname0.0080.720.749
speciesBurkholderiales_bacterium_1_1_470.0080.720.749
speciesBifidobacterium_bifidum0.0080.7360.763
familyStaphylococcaceae-0.0070.7760.803
speciesStreptococcus_phage_Sfi21-0.0070.7780.804
speciesBacteroides_caccae0.0060.7850.809
familyBurkholderiales_noname0.0060.7930.815
speciesBacteroides_faecis-0.0060.8020.823
speciesRuminococcus_torques0.0060.8110.83
familyViruses_noname0.0050.8380.854
genusViruses_noname0.0050.8380.854
speciesLachnospiraceae_bacterium_3_1_57FAA_CT10.0040.8660.881
genusParasutterella0.0040.8750.886
speciesParasutterella_excrementihominis0.0040.8750.886
speciesTuricibacter_sanguinis0.0030.8930.903
speciesRuminococcus_callidus0.0030.8950.903
speciesOdoribacter_laneus-0.0020.9360.942
genusClostridiaceae_noname0.0010.9670.969
speciesClostridiaceae_bacterium_JC1180.0010.9670.969
speciesBacteroides_fluxus0.00.9850.985
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Association of query gene abundance with clinical phenotypes:

Boxplots:


Statistics:

pheno country case_n ctrl_n case_mean ctrl_mean pvalue rank percentile
Type II diabetesDenmark752770.02799405456710.008861041556297.42554293199e-141410.462189
Liver cirrhosisChina1201140.0940181707310.02045387105374.60849321207e-05454615.2709
Crohns diseaseSpain17660.07425414717970.01341721223680.0029135560482579019.2519
Colorectal cancerAustria64350.1625341920360.03321697726610.02833007200917735.99878
Type II diabetesChina1831850.09170446983850.06369217108730.0491781036619695222.975
ObesityDenmark1691230.0124349590660.02550856590180.3406224865421516149.8537
Ulcerative colitisSpain78660.005583599305510.01341721223680.5527500679532039967.2923
Type II diabetesSweden53920.02165724241460.02475949818490.7023222398422146072.6719
Rheumatoid arthritisChina127980.05191164269450.0451211700270.7062103588522246174.9025
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Citation:

Nayfach S, Fischbach MA, Pollard KS. MetaQuery: a web server for rapid annotation and quantitative analysis of specific genes in the human gut microbiome. Bioinformatics 2015;31(14). doi:10.1093/bioinformatics/btv382