MetaQuery: quantitative analysis of the human gut microbiome

Results

Estimated gene abundances and results from statistical analyses

Job details:

Submission date: 2020-11-14 09:20:03 PST
Job id & description: 2187, PA Xanthine Dehydrogenase
Query type: protein
Count queries & homologs: 1, 4
Min % identity & max e-value: 30%, 1e-5
Min % query & target coverage: 70%, 70%

Click here to download results

Table of contents:


Gut microbiome genes homologous to your query gene:

query_id target_id status kegg eggnog phylum genus query_cov target_cov percent_identity
pa1038038CompleteK13481COG4630unknownunknown98.9798.5441.61
pa1040941CompleteK13481COG4630unknownunknown97.7397.2943.82
pa1032136CompleteK13481COG4630unknownunknown98.9798.5442.15
pa1491954Lack 5'-endK13481COG4630unknownunknown73.9788.0140.86
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The abundance of your query across gut microbiome samples:




The prevalence of your query across gut microbiome samples:




Taxonomic groups correlated with your query gene:

tax_level tax_name spearman_rho pvalue qvalue
genusPrevotella0.1673.23e-131.52e-10
genusOxalobacter0.1612.28e-123.59e-10
speciesOxalobacter_formigenes0.1612.28e-123.59e-10
familyOxalobacteraceae0.163.41e-124.02e-10
familyPrevotellaceae0.1532.59e-112.44e-09
speciesPrevotella_copri0.1514.71e-113.71e-09
genusDesulfovibrio0.1337.03e-093.58e-07
phylumSynergistetes0.1338.34e-093.58e-07
classSynergistia0.1338.34e-093.58e-07
orderSynergistales0.1338.34e-093.58e-07
familySynergistaceae0.1338.34e-093.58e-07
speciesAlistipes_senegalensis0.131.83e-087.2e-07
genusPyramidobacter0.1221.14e-073.84e-06
speciesPyramidobacter_piscolens0.1221.14e-073.84e-06
genusMethanobrevibacter0.1211.71e-075.38e-06
speciesMethanobrevibacter_smithii0.1192.58e-077.61e-06
classMethanobacteria0.1183.1e-077.7e-06
orderMethanobacteriales0.1183.1e-077.7e-06
familyMethanobacteriaceae0.1183.1e-077.7e-06
speciesPrevotella_stercorea0.1121.17e-062.76e-05
phylumEuryarchaeota0.1121.26e-062.83e-05
speciesMethanobrevibacter_unclassified0.1111.55e-063.33e-05
speciesParaprevotella_xylaniphila0.111.95e-064e-05
genusEggerthella-0.1064.74e-069.32e-05
speciesBacteroides_plebeius0.1055.4e-060.000102
speciesEggerthella_unclassified-0.1046.19e-060.000112
speciesEubacterium_biforme0.1046.58e-060.000115
speciesBacteroides_intestinalis0.1011.24e-050.000209
orderPasteurellales0.11.45e-050.000228
familyPasteurellaceae0.11.45e-050.000228
speciesRuminococcus_callidus0.0982.09e-050.00031
speciesDesulfovibrio_desulfuricans0.0982.1e-050.00031
speciesHaemophilus_parainfluenzae0.0972.62e-050.000369
speciesBifidobacterium_angulatum0.0972.66e-050.000369
genusHaemophilus0.0972.9e-050.000391
speciesLachnospiraceae_bacterium_1_4_56FAA-0.0945.01e-050.000639
speciesBacteroides_eggerthii0.0945.08e-050.000639
speciesRuminococcus_champanellensis0.0935.37e-050.000639
speciesLachnospiraceae_bacterium_1_1_57FAA0.0935.48e-050.000639
speciesDesulfovibrio_piger0.0935.49e-050.000639
speciesClostridium_sp_L2_500.0935.55e-050.000639
speciesLactobacillus_ruminis0.0926.58e-050.000739
speciesRoseburia_inulinivorans0.0918.29e-050.000905
genusEnterobacter0.0918.44e-050.000905
speciesButyrivibrio_crossotus0.0860.000190.00192
familyBacteroidaceae-0.0860.0001910.00192
genusBacteroides-0.0860.0001910.00192
genusParaprevotella0.0850.0002280.00219
speciesRoseburia_hominis0.0850.0002360.00219
genusPhascolarctobacterium0.0850.0002370.00219
speciesPhascolarctobacterium_succinatutens0.0850.0002370.00219
speciesEnterobacter_cloacae0.0850.0002420.0022
speciesParabacteroides_goldsteinii0.0840.000280.00249
speciesStreptococcus_infantarius0.0830.0003040.00266
speciesMegasphaera_elsdenii0.0820.0003810.00327
speciesEubacterium_eligens0.0820.0004040.00341
speciesParaprevotella_unclassified0.080.0005680.0047
speciesCitrobacter_unclassified0.0790.0005850.00476
speciesMitsuokella_multacida0.0770.0008430.00666
genusButyricimonas0.0770.0008610.00666
speciesButyricimonas_synergistica0.0770.0008610.00666
genusAnaerostipes-0.0770.0008870.00675
classGammaproteobacteria0.0750.00110.00824
speciesEggerthella_lenta-0.0750.001170.00858
genusMethanosphaera0.0750.00120.00858
speciesMethanosphaera_stadtmanae0.0750.00120.00858
speciesCitrobacter_freundii0.0740.001340.00944
speciesOdoribacter_splanchnicus0.0730.001540.0107
genusCitrobacter0.0730.00160.0109
speciesBacteroides_caccae0.0720.001780.012
speciesVeillonella_unclassified0.0720.001810.012
familySutterellaceae0.0720.001830.012
speciesBacteroides_coprocola0.0720.001870.0121
speciesBacteroides_salyersiae0.070.002620.0167
speciesClostridium_bolteae-0.0690.002680.0168
genusOdoribacter0.0690.002730.0168
genusKlebsiella0.0690.002740.0168
genusRoseburia0.0680.00310.0182
speciesAlistipes_shahii0.0680.00310.0182
speciesKlebsiella_pneumoniae0.0680.003190.0182
speciesParaprevotella_clara0.0680.003190.0182
genusFaecalibacterium0.0680.003220.0182
speciesFaecalibacterium_prausnitzii0.0680.003220.0182
speciesBacteroides_uniformis-0.0680.003240.0182
phylumProteobacteria0.0680.00340.0186
genusCoprobacillus-0.0680.00340.0186
orderBurkholderiales0.0680.003430.0186
classBetaproteobacteria0.0670.003710.0198
genusButyrivibrio0.0670.003740.0198
speciesLachnospiraceae_bacterium_5_1_63FAA-0.0670.00390.0205
speciesEscherichia_unclassified0.0660.004430.023
speciesBacteroides_massiliensis0.0650.005020.0258
genusCatenibacterium0.0640.005670.0285
speciesCatenibacterium_mitsuokai0.0640.005670.0285
speciesBifidobacterium_longum-0.0640.005830.0288
speciesCoprobacillus_unclassified-0.0640.005850.0288
genusVeillonella0.0630.006570.032
speciesClostridium_perfringens0.0620.007790.0375
speciesClostridium_ramosum-0.0610.007890.0376
speciesAnaerotruncus_colihominis-0.0610.008580.0405
genusActinomyces-0.060.009670.0451
speciesBacteroides_finegoldii0.060.009750.0451
speciesVeillonella_parvula0.0590.01010.0463
speciesDialister_invisus-0.0590.01040.0472
speciesDorea_unclassified-0.0590.01050.0472
speciesRuminococcus_gnavus-0.0590.01090.0485
speciesBlautia_hydrogenotrophica-0.0580.01140.0489
orderEnterobacteriales0.0580.01150.0489
familyEnterobacteriaceae0.0580.01150.0489
speciesAcidaminococcus_fermentans0.0580.01150.0489
speciesBacteroides_clarus0.0580.01150.0489
speciesBacteroides_faecis0.0580.01220.0514
speciesParabacteroides_merdae0.0580.01270.053
genusDialister-0.0570.0130.0538
speciesRuminococcus_sp_5_1_39BFAA-0.0570.01320.0542
familyActinomycetaceae-0.0570.01350.0549
speciesAnaerostipes_hadrus-0.0570.01430.057
genusSutterellaceae_unclassified0.0570.01450.057
speciesAnaerotruncus_unclassified0.0560.01450.057
speciesStreptococcus_thermophilus-0.0570.01450.057
genusPorphyromonas0.0560.01490.0581
speciesClostridium_symbiosum-0.0560.01630.0631
familyAcidaminococcaceae0.0550.01690.0649
genusEscherichia0.0550.01740.0662
genusParasutterella0.0540.0190.0712
speciesParasutterella_excrementihominis0.0540.0190.0712
speciesClostridium_clostridioforme-0.0540.01930.0717
familyBacteroidales_noname0.0530.0220.0799
genusBacteroidales_noname0.0530.0220.0799
speciesBacteroidales_bacterium_ph80.0530.0220.0799
speciesCoprococcus_eutactus0.0530.02230.0803
speciesEscherichia_coli0.0530.02260.0808
speciesErysipelotrichaceae_bacterium_3_1_53-0.0520.02520.0894
genusErysipelotrichaceae_noname0.0510.02780.0972
genusFlavonifractor-0.0510.0280.0972
speciesFlavonifractor_plautii-0.0510.0280.0972
speciesBacteroides_ovatus-0.050.0320.11
speciesOlsenella_unclassified0.0490.03240.111
genusBlautia-0.0480.03820.13
speciesAlistipes_finegoldii0.0480.03950.133
speciesLachnospiraceae_bacterium_2_1_58FAA-0.0470.04350.144
genusOlsenella0.0470.04360.144
speciesCoprococcus_sp_ART55_10.0470.04360.144
speciesBacteroides_barnesiae0.0460.04730.155
speciesMegasphaera_unclassified0.0460.04760.155
genusLactobacillus0.0460.04810.156
genusSutterella0.0450.05130.164
speciesBifidobacterium_catenulatum0.0450.05140.164
speciesMegamonas_unclassified0.0450.05170.164
speciesOscillibacter_sp_KLE_1745-0.0450.05260.164
genusMegamonas0.0450.05270.164
speciesEubacterium_siraeum0.0450.05270.164
genusMegasphaera0.0450.05330.164
phylumFirmicutes0.0440.05550.17
speciesRoseburia_intestinalis0.0440.05740.175
speciesBlautia_producta-0.0440.05940.18
familyLactobacillaceae0.0440.05990.18
speciesProteus_mirabilis0.0430.06310.189
speciesClostridium_sp_KLE_17550.0430.06430.189
familyLachnospiraceae0.0430.06480.189
phylumVerrucomicrobia0.0420.06650.189
classVerrucomicrobiae0.0420.06650.189
orderVerrucomicrobiales0.0420.06650.189
familyVerrucomicrobiaceae0.0420.06650.189
genusAkkermansia0.0420.06650.189
speciesAkkermansia_muciniphila0.0420.06650.189
classClostridia0.0420.06820.191
orderClostridiales0.0420.06820.191
speciesBacteroides_coprophilus0.0420.06840.191
speciesBifidobacterium_breve-0.0420.07180.199
speciesSubdoligranulum_unclassified0.0410.07570.209
genusSubdoligranulum0.0410.07740.212
speciesParabacteroides_johnsonii0.0410.07920.214
classDeltaproteobacteria0.040.08010.214
orderDesulfovibrionales0.040.08010.214
familyDesulfovibrionaceae0.040.08010.214
speciesRoseburia_unclassified-0.040.08020.214
speciesErysipelotrichaceae_bacterium_6_1_45-0.040.08070.214
genusMitsuokella0.040.08120.214
genusBifidobacterium-0.040.08230.216
speciesBacteroides_dorei-0.040.08520.221
orderBifidobacteriales-0.040.08590.221
familyBifidobacteriaceae-0.040.08590.221
speciesMitsuokella_unclassified0.040.08620.221
speciesMegamonas_funiformis0.040.08650.221
speciesVeillonella_atypica0.040.08750.222
speciesPropionibacterium_freudenreichii-0.0390.08860.224
classErysipelotrichia0.0390.09070.225
orderErysipelotrichales0.0390.09070.225
familyErysipelotrichaceae0.0390.09070.225
speciesStreptococcus_anginosus0.0390.09120.225
speciesSutterella_parvirubra0.0390.0920.226
speciesStreptococcus_phage_Sfi210.0390.09240.226
speciesKlebsiella_oxytoca0.0390.09380.228
speciesSutterella_wadsworthensis0.0390.09470.229
speciesLactococcus_phage_P680-0.0390.09510.229
speciesClostridium_leptum-0.0380.09880.237
speciesLachnospiraceae_bacterium_3_1_46FAA0.0380.1010.241
speciesVeillonella_dispar0.0380.1020.241
genusActinobacillus0.0380.1030.241
speciesActinobacillus_unclassified0.0380.1030.241
speciesLactobacillus_mucosae0.0380.1030.241
genusCoprococcus0.0370.1050.244
speciesStreptococcus_sanguinis-0.0370.1070.248
speciesHoldemania_sp_AP2-0.0370.1080.249
speciesClostridiales_bacterium_1_7_47FAA-0.0370.1090.25
genusPropionibacterium-0.0370.110.251
speciesCoprococcus_catus0.0370.1110.252
orderCaudovirales-0.0370.1130.254
speciesAggregatibacter_segnis0.0370.1130.254
genusAnaerotruncus0.0360.1160.259
speciesFusobacterium_varium-0.0360.1170.26
speciesAcidaminococcus_intestini0.0360.120.266
speciesOdoribacter_unclassified-0.0360.1230.271
speciesBacteroides_fluxus0.0360.1250.272
speciesErysipelotrichaceae_bacterium_2_2_44A-0.0350.1250.272
speciesBacteroides_sp_3_1_190.0350.1250.272
familyEnterococcaceae-0.0350.1270.272
familySiphoviridae-0.0350.1270.272
speciesBacteroides_stercoris0.0350.1270.272
genusCampylobacter0.0350.1290.274
speciesClostridium_bartlettii0.0350.1290.274
speciesEubacterium_sp_3_1_31-0.0350.130.275
genusBurkholderiales_noname0.0350.1320.277
speciesBurkholderiales_bacterium_1_1_470.0350.1320.277
phylumActinobacteria-0.0350.1330.277
classActinobacteria-0.0350.1330.277
speciesAlistipes_sp_HGB5-0.0350.1350.277
familyCampylobacteraceae0.0350.1360.277
genusEnterococcus-0.0340.1360.277
speciesHaemophilus_sputorum0.0340.1360.277
speciesOscillibacter_sp_KLE_1728-0.0340.1360.277
speciesParabacteroides_unclassified-0.0340.140.284
familyBurkholderiales_noname0.0340.1410.284
speciesLachnospiraceae_bacterium_9_1_43BFAA-0.0340.1420.285
speciesClostridium_citroniae-0.0340.1430.286
speciesClostridium_asparagiforme-0.0340.1460.291
familyViruses_noname0.0330.1510.297
genusViruses_noname0.0330.1510.297
speciesEnterobacteria_phage_HK5440.0330.1510.297
genusStaphylococcus0.0330.1560.306
speciesLactobacillus_gasseri0.0330.1570.306
genusAggregatibacter0.0320.1610.313
classBacilli0.0320.1640.317
speciesRuminococcus_obeum-0.0320.1670.322
speciesPrevotella_buccae0.0320.1680.322
orderLactobacillales0.0320.1730.326
familyRuminococcaceae0.0320.1730.326
speciesLachnospiraceae_bacterium_6_1_63FAA-0.0320.1730.326
phylumBacteroidetes-0.0310.1740.326
classBacteroidia-0.0310.1740.326
orderBacteroidales-0.0310.1740.326
speciesParabacteroides_sp_D130.0310.1770.33
familyBacillales_noname-0.0310.1810.335
genusGemella-0.0310.1810.335
speciesBacteroides_pectinophilus0.0310.1830.337
genusLambdalikevirus0.0310.1860.34
genusRuminococcus-0.0310.1860.34
speciesLactobacillus_sanfranciscensis0.030.1890.343
speciesPorphyromonas_asaccharolytica0.030.1890.343
speciesLactobacillus_delbrueckii-0.030.1950.353
classEpsilonproteobacteria0.0290.2050.367
orderCampylobacterales0.0290.2050.367
familyStaphylococcaceae0.0290.2050.367
orderCoriobacteriales-0.0290.2090.371
familyCoriobacteriaceae-0.0290.2090.371
speciesBacteroides_fragilis-0.0290.2110.373
speciesLactobacillus_casei_paracasei-0.0290.2180.384
speciesEubacterium_dolichum-0.0280.2220.388
speciesBacteroides_xylanisolvens0.0280.2220.388
speciesKlebsiella_unclassified0.0280.2280.396
speciesMegamonas_rupellensis0.0280.2280.396
speciesLactococcus_phage_bIL67-0.0280.2320.401
speciesLactobacillus_salivarius0.0270.2410.415
speciesEnterobacter_aerogenes0.0270.2460.422
speciesFusobacterium_mortiferum0.0270.2490.426
genusSlackia0.0270.2510.428
speciesAnaerostipes_unclassified-0.0260.2520.428
phylumViruses_noname-0.0260.2550.428
classViruses_noname-0.0260.2550.428
speciesLactobacillus_vaginalis0.0260.2550.428
familyPropionibacteriaceae-0.0260.2560.428
speciesFusobacterium_ulcerans-0.0260.260.434
speciesWeissella_cibaria0.0260.2640.437
speciesBacteroides_sp_4_3_47FAA-0.0260.2640.437
classNegativicutes0.0250.2710.446
orderSelenomonadales0.0250.2710.446
speciesErysipelotrichaceae_bacterium_5_2_54FAA-0.0250.2720.446
speciesStreptococcus_parasanguinis-0.0250.2730.446
speciesBifidobacterium_bifidum0.0250.2740.446
speciesEggerthella_sp_1_3_56FAA-0.0250.2760.446
speciesBacteroides_sp_1_1_6-0.0250.2760.446
speciesLeuconostoc_lactis0.0250.2790.449
speciesEubacterium_hallii-0.0250.2840.456
genusHoldemania-0.0240.2920.467
speciesKlebsiella_sp_MS_92_3-0.0240.3010.48
genusSiphoviridae_noname-0.0240.3020.48
speciesSlackia_piriformis0.0240.3030.48
genusProteus0.0240.3090.488
speciesBifidobacterium_animalis-0.0230.310.488
genusTunalikevirus-0.0230.330.517
genusParabacteroides-0.0220.3320.519
orderActinomycetales-0.0220.3370.525
familyPeptostreptococcaceae0.0220.3380.525
speciesStreptococcus_pasteurianus-0.0220.3390.525
speciesKlebsiella_phage_KP36-0.0220.3460.532
speciesPeptostreptococcaceae_noname_unclassified-0.0220.3460.532
speciesMegamonas_hypermegale0.0220.3490.533
speciesAlistipes_putredinis0.0220.3490.533
genusPeptostreptococcus0.0210.3550.541
speciesGemella_morbillorum-0.0210.3610.546
speciesStreptococcus_australis0.0210.3610.546
speciesBacteroides_oleiciplenus0.0210.3640.547
speciesLactococcus_lactis-0.0210.3640.547
speciesAcidaminococcus_unclassified-0.0210.3740.56
speciesRuminococcus_lactaris0.020.3770.563
speciesParabacteroides_distasonis-0.020.3870.576
genusLachnospiraceae_noname0.020.3880.576
speciesStreptococcus_lutetiensis0.020.3920.58
familyEubacteriaceae0.0190.40.588
genusEubacterium0.0190.40.588
speciesLachnospiraceae_bacterium_2_1_46FAA-0.0190.4090.6
speciesLactobacillus_reuteri0.0190.4120.602
speciesBacteroides_cellulosilyticus0.0190.4130.602
genusCoriobacteriaceae_noname-0.0190.420.61
genusGordonibacter-0.0180.4310.622
speciesGordonibacter_pamelaeae-0.0180.4310.622
speciesBifidobacterium_pseudocatenulatum0.0180.4360.627
speciesMegasphaera_micronuciformis0.0180.4370.627
speciesCoriobacteriaceae_bacterium_phI-0.0180.4410.63
speciesCollinsella_unclassified-0.0180.4420.63
speciesParabacteroides_sp_20_30.0180.4440.631
genusClostridiales_noname-0.0180.4470.633
speciesPeptostreptococcus_stomatis0.0180.4480.633
speciesCoprococcus_comes0.0170.4530.637
speciesHoldemania_filiformis-0.0170.4540.637
genusAcidaminococcus0.0170.4550.637
speciesPorphyromonas_uenonis0.0170.4640.648
speciesLachnospiraceae_bacterium_5_1_57FAA-0.0170.4660.649
speciesWeissella_confusa0.0170.4690.651
genusDorea-0.0170.4730.655
speciesLactobacillus_fermentum0.0160.4810.663
familyClostridiales_noname-0.0160.4820.663
genusSolobacterium-0.0160.4920.673
speciesSolobacterium_moorei-0.0160.4920.673
speciesEubacterium_rectale0.0160.4940.674
familyPorphyromonadaceae-0.0160.4970.676
speciesLactobacillus_plantarum0.0160.4990.677
familyClostridiales_Family_XI_Incertae_Sedis0.0160.5010.678
speciesClostridium_spiroforme-0.0150.5060.68
familyOscillospiraceae-0.0150.5070.68
genusOscillibacter-0.0150.5070.68
speciesAlistipes_onderdonkii0.0150.5150.686
speciesBacteroides_vulgatus-0.0150.5150.686
speciesPrevotella_bivia-0.0150.5160.686
speciesCoprobacillus_sp_D6-0.0150.5180.686
speciesLactobacillus_acidophilus-0.0150.5190.686
speciesClostridium_sp_ATCC_BAA_4420.0150.5220.688
speciesOdoribacter_laneus0.0150.5250.69
speciesHaemophilus_paraphrohaemolyticus0.0150.5280.69
speciesLactobacillus_rhamnosus-0.0150.5280.69
genusPseudoflavonifractor-0.0140.5330.693
speciesPseudoflavonifractor_capillosus-0.0140.5330.693
genusLactococcus-0.0140.5380.698
speciesDorea_formicigenerans-0.0140.5430.702
speciesRuminococcus_sp_JC304-0.0140.5480.707
speciesClostridium_nexile0.0140.5550.714
speciesBilophila_unclassified0.0130.5610.72
speciesCollinsella_tanakaei0.0130.5680.722
familyPodoviridae-0.0130.5690.722
genusSuccinatimonas0.0130.5690.722
speciesSuccinatimonas_hippei0.0130.5690.722
speciesSubdoligranulum_sp_4_3_54A2FAA-0.0130.5720.724
speciesRuminococcus_torques-0.0130.5740.724
speciesHoldemania_unclassified0.0130.5820.733
genusClostridium0.0130.5870.737
speciesEubacterium_cylindroides-0.0130.5890.737
speciesCoprobacillus_sp_29_1-0.0120.5940.739
speciesCollinsella_intestinalis-0.0120.5940.739
genusFusobacterium-0.0120.5950.739
familySuccinivibrionaceae0.0120.5990.741
genusButyricicoccus-0.0120.6010.741
speciesButyricicoccus_pullicaecorum-0.0120.6010.741
familyFusobacteriaceae-0.0120.6040.742
speciesBacteroides_salanitronis0.0120.6060.743
speciesEubacterium_limosum0.0120.6110.747
genusPeptostreptococcaceae_noname0.0120.6180.752
speciesErysipelotrichaceae_bacterium_21_3-0.0120.6180.752
genusBilophila0.0110.6220.755
phylumFusobacteria-0.0110.6390.767
classFusobacteriia-0.0110.6390.767
orderFusobacteriales-0.0110.6390.767
speciesEubacterium_ramulus-0.0110.640.767
familyClostridiaceae0.0110.6420.767
speciesBilophila_wadsworthia0.0110.6420.767
speciesStreptococcus_vestibularis-0.0110.6460.77
speciesLactobacillus_oris0.0110.6490.772
genusParvimonas0.010.6530.772
speciesParvimonas_unclassified0.010.6530.772
orderBacillales-0.010.6630.78
speciesLactococcus_garvieae0.010.6630.78
orderPseudomonadales-0.010.6660.782
speciesBacteroides_thetaiotaomicron-0.010.6720.787
speciesDorea_longicatena0.010.6770.791
speciesEnterococcus_faecalis-0.010.6810.794
speciesEnterococcus_faecium-0.0090.6880.8
speciesLactococcus_phage_jm2-0.0090.7030.815
orderViruses_noname0.0090.7060.817
speciesStreptococcus_gordonii-0.0090.7120.821
genusBarnesiella0.0080.7150.821
speciesBarnesiella_intestinihominis0.0080.7150.821
speciesAlistipes_unclassified-0.0080.7210.825
genusMorganella0.0080.7240.825
speciesMorganella_morganii0.0080.7240.825
familyLeuconostocaceae-0.0080.7310.831
genusWeissella0.0080.7370.834
familyRikenellaceae0.0080.7390.834
genusAlistipes0.0080.7390.834
genusClostridiaceae_noname-0.0070.7670.862
speciesClostridiaceae_bacterium_JC118-0.0070.7670.862
speciesFusobacterium_nucleatum-0.0060.7870.882
speciesLachnospiraceae_bacterium_7_1_58FAA0.0060.7910.884
speciesCollinsella_aerofaciens0.0060.7930.884
familyMyoviridae-0.0060.7950.884
genusLeuconostoc0.0060.7960.884
genusC2likevirus-0.0060.8030.888
speciesOscillibacter_unclassified-0.0060.8030.888
familyVeillonellaceae0.0060.810.893
speciesStreptococcus_salivarius0.0050.8160.897
speciesDialister_succinatiphilus0.0050.8170.897
speciesButyrivibrio_unclassified-0.0050.8290.905
speciesTuricibacter_unclassified0.0050.830.905
speciesLactobacillus_crispatus0.0050.8310.905
genusStreptococcus-0.0050.8320.905
speciesBacteroides_nordii-0.0050.840.911
speciesPeptostreptococcus_anaerobius0.0050.8420.911
speciesC2likevirus_unclassified-0.0050.8440.911
speciesLactococcus_phage_936_sensu_lato0.0050.8450.911
speciesLactobacillus_amylovorus0.0040.8520.914
familyMicrococcaceae-0.0040.8550.914
genusRuminococcaceae_noname-0.0040.8560.914
speciesRuminococcaceae_bacterium_D16-0.0040.8560.914
genusRothia-0.0040.8580.914
genusAdlercreutzia-0.0040.870.923
speciesAdlercreutzia_equolifaciens-0.0040.870.923
speciesCampylobacter_concisus0.0030.8810.932
speciesLactococcus_phage_phi7-0.0030.8830.932
speciesBacteroides_sp_2_1_22-0.0030.8880.934
genusCoprobacter0.0030.890.934
speciesCoprobacter_fastidiosus0.0030.890.934
speciesRuminococcus_bromii0.0030.8930.935
speciesStreptococcus_mutans0.0030.8980.938
familyStreptococcaceae-0.0030.90.938
genusPantoea0.0030.9040.938
speciesPantoea_unclassified0.0030.9040.938
genusTuricibacter0.0030.9080.94
genusPeptoniphilus0.0020.9140.944
speciesBifidobacterium_dentium0.0020.9230.951
genusAcidaminococcaceae_unclassified-0.0020.9320.958
speciesLachnospiraceae_bacterium_3_1_57FAA_CT10.0020.9340.958
speciesRothia_mucilaginosa-0.0020.9380.96
speciesEubacterium_ventriosum0.0020.9480.968
speciesTuricibacter_sanguinis-0.0010.9510.968
speciesAlistipes_sp_AP11-0.0010.9530.968
genusCollinsella-0.0010.9540.968
speciesLachnospiraceae_bacterium_8_1_57FAA-0.0010.9590.971
orderAeromonadales-0.0010.9650.975
speciesBifidobacterium_adolescentis0.0010.9760.984
speciesStreptococcus_mitis_oralis_pneumoniae0.00.9830.989
genusMyoviridae_noname0.00.9850.989
speciesClostridium_hathewayi0.00.990.991
speciesAlistipes_indistinctus0.00.9910.991
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Association of query gene abundance with clinical phenotypes:

Boxplots:


Statistics:

pheno country case_n ctrl_n case_mean ctrl_mean pvalue rank percentile
Rheumatoid arthritisChina127981.09174284454e-056.49058796792e-050.005475389742176782.26098
Ulcerative colitisSpain78663.36655986881e-060.0001882790622810.018022353335826518.74513
Colorectal cancerAustria64356.70703787992e-060.00.3001410587371244442.1031
Type II diabetesChina1831850.0002748973431323.26363529056e-050.3998205930831887062.3616
Type II diabetesSweden53920.03.07303600643e-060.4503027988091497750.7179
Crohns diseaseSpain17663.01038895202e-070.0001882790622810.5156514076952365478.65
ObesityDenmark1691230.0006785351854850.0002879365759220.6490379420232277374.8841
Type II diabetesDenmark752770.000335649900810.0005201149005710.7789765718142636986.4359
Liver cirrhosisChina1201140.0001322613548318.60310333711e-050.8753945895862834695.2199
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Citation:

Nayfach S, Fischbach MA, Pollard KS. MetaQuery: a web server for rapid annotation and quantitative analysis of specific genes in the human gut microbiome. Bioinformatics 2015;31(14). doi:10.1093/bioinformatics/btv382