MetaQuery: quantitative analysis of the human gut microbiome

Results

Estimated gene abundances and results from statistical analyses

Job details:

Submission date: 2021-01-24 10:03:16 PST
Job id & description: 2391, purine11
Query type: protein
Count queries & homologs: 100, 100
Min % identity & max e-value: 100%, 1e-5
Min % query & target coverage: 95%, 95%

Click here to download results

Table of contents:


Gut microbiome genes homologous to your query gene:

query_id target_id status kegg eggnog phylum genus query_cov target_cov percent_identity
MH0333_GL00829693317414CompleteK05810NOG134282BacteroidetesBacteroides100.0100.0100.0
T2D-135A_GL00455023309572CompleteK05810COG1496Bacteroidetesunknown100.0100.0100.0
MH0357_GL01619533317816CompleteK05810COG1496unknownunknown100.0100.0100.0
NOF011_GL00431743324866Lack 5'-endK00772COG0005unknownunknown100.0100.0100.0
O2.UC18-1_GL01929843320483Lack 5'-endK00772COG0005unknownunknown100.0100.0100.0
MH0003_GL00134733312256CompleteK05810COG1496unknownunknown100.0100.0100.0
MH0037_GL00114553312874CompleteK05810NOG134282BacteroidetesBacteroides100.0100.0100.0
MH0046_GL00204343312974CompleteK05810COG1496unknownunknown100.0100.0100.0
T2D-10A_GL01175403325607CompleteK03784COG0813unknownunknown100.0100.0100.0
T2D-192A_GL00618473310402CompleteK05810COG1496FirmicutesPhascolarctobacterium100.0100.0100.0
457421.CBFG_038813311971CompleteK03783COG0005Firmicutesunknown100.0100.0100.0
159632143-stool1_revised3310911CompleteK03783COG0005unknownunknown100.0100.0100.0
MH0055_GL00558433313111CompleteK05810COG1496unknownunknown100.0100.0100.0
MH0430_GL01141463319343CompleteK03783COG0005Bacteroidetesunknown100.0100.0100.0
O2.CD1-0-PT_GL00558643320102CompleteK05810COG1496unknownunknown100.0100.0100.0
160319967-stool1_revised3310972Lack 5'-endK05810COG1496unknownunknown100.0100.0100.0
MH0222_GL01980853315721CompleteK03783COG0005unknownunknown100.0100.0100.0
SZEY-38A_GL00072573325417CompleteK03783COG0005Bacteroidetesunknown100.0100.0100.0
159753524-stool1_revised3327216CompleteK05810COG1496unknownunknown100.0100.0100.0
MH0314_GL00719383317075CompleteK05810COG1496unknownunknown100.0100.0100.0
158337416-stool2_revised3310483CompleteK03783COG0005unknownunknown100.0100.0100.0
MH0443_GL00977473319715CompleteK03783COG0005Bacteroidetesunknown100.0100.0100.0
MH0448_GL01797463319867CompleteK03783COG0005Bacteroidetesunknown100.0100.0100.0
T2D-57A_GL00869143309970CompleteK05810COG1496unknownunknown100.0100.0100.0
159571453-stool1_revised3327123CompleteK03783COG0005Bacteroidetesunknown100.0100.0100.0
MH0247_GL00201593316104CompleteK03783COG0005BacteroidetesAlistipes100.0100.0100.0
MH0257_GL00515223316250CompleteK03783COG0005Bacteroidetesunknown100.0100.0100.0
O2.UC36-0_GL01869873320950CompleteK05810COG1496unknownunknown100.0100.0100.0
158802708-stool1_revised3310662CompleteK03783COG0005unknownunknown100.0100.0100.0
764588959-stool1_revised3311591CompleteK03783COG0005unknownunknown100.0100.0100.0
MH0055_GL00659133313117CompleteK03783COG0005Bacteroidetesunknown100.0100.0100.0
V1.UC17-0_GL00098733323376CompleteK03783COG0005Bacteroidetesunknown100.0100.0100.0
1069533.Sinf_07053311773CompleteK03783COG0005FirmicutesStreptococcus100.0100.0100.0
158499257-stool1_revised3310593CompleteK03783COG0005unknownunknown100.0100.0100.0
MH0069_GL00032593313250CompleteK03783COG0005BacteroidetesBacteroides100.0100.0100.0
MH0415_GL00584213319043CompleteK03783COG0005unknownunknown100.0100.0100.0
NOF010_GL00015133324853CompleteK03783COG0005Bacteroidetesunknown100.0100.0100.0
T2D-135A_GL00905113325785CompleteK03783COG0005BacteroidetesBacteroides100.0100.0100.0
T2D-73A_GL00461813326350CompleteK03783COG0005BacteroidetesBacteroides100.0100.0100.0
V1.UC38-0_GL01047503323685CompleteK05810COG1496unknownunknown100.0100.0100.0
MH0002_GL00311073312226CompleteK03783COG0005BacteroidetesBacteroides100.0100.0100.0
MH0003_GL00948753312292CompleteK03783COG0005BacteroidetesBacteroides100.0100.0100.0
MH0004_GL00328963312316CompleteK03783COG0005BacteroidetesBacteroides100.0100.0100.0
MH0011_GL01032153312522CompleteK03783COG0005BacteroidetesBacteroides100.0100.0100.0
MH0025_GL00659273312772CompleteK03783COG0005BacteroidetesBacteroides100.0100.0100.0
MH0052_GL00457363313029CompleteK03783COG0005BacteroidetesBacteroides100.0100.0100.0
MH0054_GL00819203313080CompleteK03783COG0005BacteroidetesBacteroides100.0100.0100.0
MH0057_GL00097123313124CompleteK03783COG0005Bacteroidetesunknown100.0100.0100.0
MH0079_GL00387073313341CompleteK03783COG0005BacteroidetesBacteroides100.0100.0100.0
MH0113_GL00928213313891CompleteK03783COG0005Bacteroidetesunknown100.0100.0100.0
MH0187_GL00588593314978CompleteK03783COG0005Bacteroidetesunknown100.0100.0100.0
MH0189_GL01130623315124CompleteK03783COG0005Bacteroidetesunknown100.0100.0100.0
MH0192_GL00966973315202CompleteK03783COG0005Bacteroidetesunknown100.0100.0100.0
MH0196_GL00903173315284CompleteK03783COG0005Bacteroidetesunknown100.0100.0100.0
MH0198_GL01423793315383CompleteK03783COG0005Bacteroidetesunknown100.0100.0100.0
MH0239_GL00868373315979CompleteK03783COG0005Bacteroidetesunknown100.0100.0100.0
MH0243_GL00039893316015CompleteK03783COG0005BacteroidetesBacteroides100.0100.0100.0
MH0243_GL00348443316019CompleteK03783COG0005unknownunknown100.0100.0100.0
MH0264_GL00334493316386CompleteK03783COG0005unknownunknown100.0100.0100.0
MH0281_GL01320903316734CompleteK03783COG0005BacteroidetesBacteroides100.0100.0100.0
MH0314_GL00134103317064CompleteK03783COG0005BacteroidetesBacteroides100.0100.0100.0
MH0321_GL00251223317215CompleteK03783COG0005BacteroidetesBacteroides100.0100.0100.0
MH0328_GL01425703317302CompleteK03783COG0005Bacteroidetesunknown100.0100.0100.0
MH0333_GL00323013317397CompleteK03783COG0005BacteroidetesBacteroides100.0100.0100.0
MH0359_GL00473143317874CompleteK03783COG0005BacteroidetesAlistipes100.0100.0100.0
MH0381_GL00385263318361CompleteK03783COG0005BacteroidetesBacteroides100.0100.0100.0
MH0435_GL00949443319522CompleteK03783COG0005Bacteroidetesunknown100.0100.0100.0
NLF006_GL00070873324678CompleteK03783COG0005BacteroidetesBacteroides100.0100.0100.0
NOF013_GL00322823324875CompleteK03783COG0005BacteroidetesBacteroides100.0100.0100.0
NOF013_GL00464943324877CompleteK03783COG0005Bacteroidetesunknown100.0100.0100.0
O2.UC24-1_GL01767833320659CompleteK03783COG0005Bacteroidetesunknown100.0100.0100.0
T2D-113A_GL00244143325631CompleteK03783COG0005BacteroidetesBacteroides100.0100.0100.0
T2D-133A_GL00474773325751CompleteK03783COG0005BacteroidetesBacteroides100.0100.0100.0
T2D-135A_GL01145983325794CompleteK03783COG0005BacteroidetesBacteroides100.0100.0100.0
V1.CD38-0_GL01252663322126CompleteK03783COG0005BacteroidetesBacteroides100.0100.0100.0
765560005-stool1_revised3311682CompleteK03783COG0005unknownunknown100.0100.0100.0
MH0004_GL00185853312307CompleteK03783COG0005BacteroidetesBacteroides100.0100.0100.0
MH0011_GL00520433312502CompleteK03783COG0005BacteroidetesBacteroides100.0100.0100.0
MH0033_GL00522533312847CompleteK03783COG0005Bacteroidetesunknown100.0100.0100.0
MH0037_GL00472743312886CompleteK03783COG0005BacteroidetesBacteroides100.0100.0100.0
MH0055_GL00491323313108CompleteK03783COG0005BacteroidetesBacteroides100.0100.0100.0
MH0142_GL00649793314334CompleteK03783COG0005unknownunknown100.0100.0100.0
MH0143_GL00145193314352CompleteK03783COG0005BacteroidetesBacteroides100.0100.0100.0
MH0267_GL00897343316441CompleteK03783COG0005BacteroidetesBacteroides100.0100.0100.0
763597684-stool1_revised3311296CompleteK03783COG0005unknownunknown100.0100.0100.0
888825.HMPREF9398_12043312187CompleteK03783COG0005FirmicutesStreptococcus100.0100.0100.0
V1.UC41-0_GL00266063323788CompleteK03783COG0005unknownunknown100.0100.0100.0
158499257-stool1_revised3310595CompleteK03783COG0005unknownunknown100.0100.0100.0
158499257-stool1_revised3310584CompleteK03783COG0005unknownunknown100.0100.0100.0
388919.SSA_12593311836CompleteK03783COG0005FirmicutesStreptococcus100.0100.0100.0
MH0003_GL00724853312282CompleteK03783COG0005unknownunknown100.0100.0100.0
MH0281_GL00882173316724CompleteK03783COG0005unknownunknown100.0100.0100.0
MH0431_GL00511353319362CompleteK03783COG0005unknownunknown100.0100.0100.0
MH0288_GL00115893316816CompleteK05810COG1496unknownunknown100.0100.0100.0
V1.CD38-0_GL00355653322120CompleteK03783COG0005FirmicutesStreptococcus100.0100.0100.0
MH0341_GL01186253317567CompleteK03783COG0005FirmicutesStreptococcus100.0100.0100.0
V1.FI06_GL01319303322608CompleteK05810COG1496unknownunknown100.0100.0100.0
V1.UC38-4_GL00890983323706CompleteK03783COG0005FirmicutesStreptococcus100.0100.0100.0
MH0003_GL00277373312265CompleteK03783COG0005FirmicutesStreptococcus100.0100.0100.0
MH0383_GL01409203318441CompleteK03783COG0005FirmicutesStreptococcus100.0100.0100.0
Click on arrows to sort table data. Shift+click to sort by multiple columns.

The abundance of your query across gut microbiome samples:




The prevalence of your query across gut microbiome samples:




Taxonomic groups correlated with your query gene:

tax_level tax_name spearman_rho pvalue qvalue
familyBacteroidaceae0.7520.00.0
genusBacteroides0.7520.00.0
phylumBacteroidetes0.6192.77e-1982.65e-196
classBacteroidia0.6192.81e-1982.65e-196
orderBacteroidales0.6192.81e-1982.65e-196
phylumFirmicutes-0.5091.45e-1231.14e-121
speciesBacteroides_vulgatus0.4932.9e-1151.96e-113
classClostridia-0.4742.32e-1051.22e-103
orderClostridiales-0.4742.32e-1051.22e-103
orderCoriobacteriales-0.4621.19e-995.11e-98
familyCoriobacteriaceae-0.4621.19e-995.11e-98
phylumActinobacteria-0.4419.57e-903.47e-88
classActinobacteria-0.4419.57e-903.47e-88
familyRuminococcaceae-0.4397.2e-892.43e-87
speciesRuminococcus_obeum-0.4255.7e-831.79e-81
genusDorea-0.4186.12e-801.81e-78
genusParabacteroides0.419.15e-772.54e-75
speciesCoprococcus_catus-0.4092.1e-765.51e-75
genusSubdoligranulum-0.4056.72e-751.67e-73
speciesBacteroides_thetaiotaomicron0.4042.72e-746.42e-73
speciesSubdoligranulum_unclassified-0.4043.17e-747.12e-73
speciesDorea_longicatena-0.3983.75e-728.05e-71
genusCoprococcus-0.3963.15e-716.46e-70
speciesBacteroides_ovatus0.3933.93e-707.73e-69
speciesBacteroides_xylanisolvens0.3818.21e-661.55e-64
speciesCollinsella_aerofaciens-0.382.41e-654.38e-64
genusCollinsella-0.3739.16e-631.6e-61
speciesEubacterium_hallii-0.3714.27e-627.2e-61
speciesCoprococcus_comes-0.3551.08e-561.76e-55
speciesBifidobacterium_adolescentis-0.3521.27e-552e-54
orderBifidobacteriales-0.3491.09e-541.61e-53
familyBifidobacteriaceae-0.3491.09e-541.61e-53
genusBifidobacterium-0.3467.19e-541.03e-52
genusRuminococcus-0.3437.04e-539.77e-52
classMethanobacteria-0.3431.26e-521.61e-51
orderMethanobacteriales-0.3431.26e-521.61e-51
familyMethanobacteriaceae-0.3431.26e-521.61e-51
genusMethanobrevibacter-0.349.18e-521.14e-50
speciesMethanobrevibacter_smithii-0.3392.01e-512.43e-50
phylumEuryarchaeota-0.3313.57e-494.21e-48
speciesDorea_formicigenerans-0.3277.65e-488.81e-47
classErysipelotrichia-0.3184e-454.29e-44
orderErysipelotrichales-0.3184e-454.29e-44
familyErysipelotrichaceae-0.3184e-454.29e-44
genusAdlercreutzia-0.3136.8e-446.98e-43
speciesAdlercreutzia_equolifaciens-0.3136.8e-446.98e-43
speciesBacteroides_stercoris0.3113.1e-433.11e-42
genusOlsenella-0.3081.75e-421.72e-41
speciesRuminococcus_sp_5_1_39BFAA-0.3051.68e-411.62e-40
familyPorphyromonadaceae0.3051.94e-411.83e-40
familyLachnospiraceae-0.3029.82e-419.09e-40
speciesOlsenella_unclassified-0.2981.38e-391.25e-38
familyActinomycetaceae-0.2971.86e-391.66e-38
genusActinomyces-0.2958.01e-397e-38
phylumVerrucomicrobia-0.2941.39e-381.09e-37
classVerrucomicrobiae-0.2941.39e-381.09e-37
orderVerrucomicrobiales-0.2941.39e-381.09e-37
familyVerrucomicrobiaceae-0.2941.39e-381.09e-37
genusAkkermansia-0.2941.39e-381.09e-37
speciesAkkermansia_muciniphila-0.2941.39e-381.09e-37
speciesStreptococcus_thermophilus-0.2941.77e-381.37e-37
classBetaproteobacteria0.2932.24e-381.71e-37
genusErysipelotrichaceae_noname-0.2923.52e-382.64e-37
orderBurkholderiales0.2893.14e-372.32e-36
speciesAnaerostipes_hadrus-0.2886.06e-374.4e-36
speciesEubacterium_ramulus-0.2852.52e-361.8e-35
speciesEubacterium_siraeum-0.285.3e-353.73e-34
genusFlavonifractor0.2791.03e-347.05e-34
speciesFlavonifractor_plautii0.2791.03e-347.05e-34
speciesClostridium_leptum-0.2773.02e-342.04e-33
phylumFusobacteria0.2764.13e-342.67e-33
classFusobacteriia0.2764.13e-342.67e-33
orderFusobacteriales0.2764.13e-342.67e-33
familySutterellaceae0.2751.03e-336.57e-33
familyFusobacteriaceae0.2733.16e-331.99e-32
orderActinomycetales-0.2716.89e-334.28e-32
genusFusobacterium0.2711e-326.13e-32
speciesBifidobacterium_longum-0.2594.16e-302.52e-29
speciesRuminococcus_gnavus0.2571.74e-291.04e-28
orderLactobacillales-0.2546.65e-293.92e-28
genusAnaerostipes-0.2546.9e-294.02e-28
speciesBacteroides_uniformis0.2531.16e-286.68e-28
classBacilli-0.2531.3e-287.39e-28
speciesErysipelotrichaceae_bacterium_21_3-0.2496.98e-283.92e-27
speciesEubacterium_biforme-0.2463.66e-272.03e-26
speciesAnaerotruncus_unclassified-0.2441.2e-266.59e-26
familyEubacteriaceae-0.2381.86e-251.01e-24
speciesBacteroides_plebeius0.2382.04e-251.09e-24
genusEubacterium-0.2372.27e-251.2e-24
speciesBacteroides_massiliensis0.2372.85e-251.49e-24
speciesRuminococcus_bromii-0.2331.54e-247.99e-24
speciesMethanobrevibacter_unclassified-0.2322.81e-241.44e-23
speciesClostridium_bolteae0.2314.81e-242.44e-23
speciesParabacteroides_distasonis0.2299.36e-244.7e-23
speciesFusobacterium_mortiferum0.2273.19e-231.58e-22
genusHaemophilus0.2256.4e-233.15e-22
speciesHaemophilus_parainfluenzae0.2256.8e-233.31e-22
orderPasteurellales0.2249.9e-234.72e-22
familyPasteurellaceae0.2249.9e-234.72e-22
speciesClostridium_citroniae0.2231.44e-226.8e-22
speciesClostridium_nexile0.2198.13e-223.8e-21
genusGordonibacter-0.2181.22e-215.59e-21
speciesGordonibacter_pamelaeae-0.2181.22e-215.59e-21
speciesFusobacterium_ulcerans0.2121.89e-208.58e-20
familyStreptococcaceae-0.2113.06e-201.38e-19
familyLactobacillaceae-0.2113.25e-201.45e-19
speciesRuminococcus_torques-0.214.59e-202.02e-19
genusBlautia-0.2097.58e-203.31e-19
speciesClostridiales_bacterium_1_7_47FAA0.2071.55e-196.71e-19
genusLactobacillus-0.2071.65e-197.08e-19
genusStreptococcus-0.2036.34e-192.7e-18
speciesStreptococcus_parasanguinis-0.1984.96e-182.09e-17
speciesBacteroides_fragilis0.1986.49e-182.71e-17
speciesFusobacterium_varium0.1951.96e-178.12e-17
genusPropionibacterium-0.1942.71e-171.11e-16
genusPseudoflavonifractor-0.1924.69e-171.88e-16
speciesPseudoflavonifractor_capillosus-0.1924.69e-171.88e-16
genusButyrivibrio-0.1924.71e-171.88e-16
speciesMitsuokella_unclassified-0.1925.04e-172e-16
genusMitsuokella-0.1918.43e-173.32e-16
phylumProteobacteria0.191.35e-165.27e-16
speciesBilophila_unclassified0.191.4e-165.42e-16
speciesBacteroides_nordii0.1891.46e-165.6e-16
speciesStreptococcus_sanguinis-0.1882.11e-168.03e-16
genusBilophila0.1882.16e-168.16e-16
speciesPropionibacterium_freudenreichii-0.1882.53e-169.48e-16
speciesLachnospiraceae_bacterium_3_1_57FAA_CT1-0.1873.4e-161.26e-15
speciesLactobacillus_rhamnosus-0.1865.13e-161.89e-15
speciesClostridium_symbiosum0.1866.05e-162.21e-15
speciesLachnospiraceae_bacterium_5_1_63FAA-0.1856.15e-162.23e-15
speciesLachnospiraceae_bacterium_3_1_46FAA-0.1841.05e-153.78e-15
genusAnaerotruncus-0.1831.68e-156.01e-15
genusLactococcus-0.1822.55e-159.05e-15
genusCatenibacterium-0.1812.64e-159.23e-15
speciesCatenibacterium_mitsuokai-0.1812.64e-159.23e-15
familyBacillales_noname-0.1812.88e-159.92e-15
genusGemella-0.1812.88e-159.92e-15
familyPeptostreptococcaceae-0.1796.72e-152.3e-14
speciesBacteroides_dorei0.1797.29e-152.48e-14
speciesButyrivibrio_crossotus-0.1771.07e-143.61e-14
genusParasutterella0.1771.38e-144.59e-14
speciesParasutterella_excrementihominis0.1771.38e-144.59e-14
genusPeptostreptococcaceae_noname-0.1762.01e-146.63e-14
genusSolobacterium-0.1752.12e-146.9e-14
speciesSolobacterium_moorei-0.1752.12e-146.9e-14
speciesParabacteroides_unclassified0.1752.25e-147.27e-14
orderBacillales-0.1734.71e-141.51e-13
speciesCoprococcus_sp_ART55_1-0.1718.35e-142.66e-13
speciesEubacterium_rectale-0.171.29e-134.09e-13
familyEnterococcaceae-0.1673.21e-131.01e-12
speciesLactococcus_lactis-0.1673.22e-131.01e-12
speciesBifidobacterium_catenulatum-0.1673.37e-131.05e-12
familyBurkholderiales_noname0.1673.72e-131.15e-12
genusDialister-0.1673.79e-131.16e-12
genusBurkholderiales_noname0.1665.47e-131.66e-12
speciesBurkholderiales_bacterium_1_1_470.1665.47e-131.66e-12
speciesBifidobacterium_animalis-0.1665.65e-131.69e-12
speciesBacteroides_salyersiae0.1665.66e-131.69e-12
genusEnterococcus-0.1648.29e-132.46e-12
speciesStreptococcus_mutans-0.1631.3e-123.83e-12
genusMethanosphaera-0.1622e-125.83e-12
speciesMethanosphaera_stadtmanae-0.1622e-125.83e-12
speciesLactococcus_phage_P680-0.1612.42e-127.01e-12
genusLeuconostoc-0.1612.89e-128.32e-12
speciesMegamonas_unclassified0.162.97e-128.5e-12
genusMegamonas0.163.14e-128.93e-12
genusSiphoviridae_noname-0.163.17e-128.96e-12
speciesLactobacillus_casei_paracasei-0.163.29e-129.24e-12
speciesBacteroides_finegoldii0.163.45e-129.64e-12
speciesMegamonas_rupellensis0.1594.66e-121.29e-11
speciesCoprococcus_eutactus-0.1586.46e-121.78e-11
familyClostridiales_noname0.1577.99e-122.19e-11
speciesBacteroides_caccae0.1561.2e-113.27e-11
speciesStreptococcus_salivarius-0.1551.53e-114.15e-11
speciesLachnospiraceae_bacterium_2_1_46FAA0.1551.73e-114.67e-11
speciesClostridium_sp_L2_50-0.1523.81e-111.02e-10
classDeltaproteobacteria0.1515.73e-111.51e-10
orderDesulfovibrionales0.1515.73e-111.51e-10
familyDesulfovibrionaceae0.1515.73e-111.51e-10
phylumViruses_noname-0.156.14e-111.6e-10
classViruses_noname-0.156.14e-111.6e-10
genusLachnospiraceae_noname-0.157.12e-111.85e-10
speciesVeillonella_dispar0.1499.39e-112.42e-10
speciesBilophila_wadsworthia0.1499.88e-112.53e-10
speciesStreptococcus_gordonii-0.1481.26e-103.21e-10
familyPropionibacteriaceae-0.1481.41e-103.58e-10
speciesKlebsiella_pneumoniae0.1471.87e-104.72e-10
genusVeillonella0.1462.58e-106.48e-10
speciesRuminococcus_sp_JC304-0.1452.62e-106.54e-10
speciesStreptococcus_vestibularis-0.1452.84e-107.06e-10
genusBarnesiella-0.1453.03e-107.45e-10
speciesBarnesiella_intestinihominis-0.1453.03e-107.45e-10
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speciesOdoribacter_splanchnicus0.1435.07e-101.22e-09
genusRothia-0.1435.41e-101.3e-09
speciesBifidobacterium_dentium-0.1426.4e-101.53e-09
familyMicrococcaceae-0.1426.5e-101.54e-09
speciesLactobacillus_delbrueckii-0.1418.19e-101.93e-09
speciesVeillonella_unclassified0.141.09e-092.56e-09
speciesAlistipes_senegalensis-0.141.34e-093.13e-09
speciesLachnospiraceae_bacterium_9_1_43BFAA0.1372.38e-095.53e-09
genusPhascolarctobacterium-0.1363.11e-097.16e-09
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speciesStreptococcus_anginosus-0.131.71e-083.77e-08
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genusClostridiales_noname0.1264.39e-089.46e-08
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genusTuricibacter-0.1255.86e-081.25e-07
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speciesParabacteroides_merdae0.1246.84e-081.43e-07
genusRoseburia0.1246.91e-081.44e-07
speciesBacteroides_oleiciplenus0.1247.3e-081.52e-07
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familyClostridiales_Family_XI_Incertae_Sedis-0.1238.97e-081.84e-07
speciesRoseburia_unclassified-0.1238.99e-081.84e-07
speciesErysipelotrichaceae_bacterium_6_1_45-0.1221.2e-072.45e-07
speciesParabacteroides_goldsteinii0.1211.41e-072.87e-07
speciesMegasphaera_micronuciformis0.121.82e-073.69e-07
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genusBacteroidales_noname-0.1173.75e-077.5e-07
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speciesBacteroides_sp_2_1_220.1164.93e-079.74e-07
speciesEggerthella_lenta-0.1147.23e-071.42e-06
speciesBacteroides_faecis0.1148.05e-071.58e-06
speciesClostridium_asparagiforme0.1121.2e-062.34e-06
speciesParabacteroides_johnsonii0.1121.33e-062.58e-06
familyLeuconostocaceae-0.1111.4e-062.71e-06
genusAggregatibacter0.1111.46e-062.81e-06
speciesPrevotella_stercorea0.1111.49e-062.86e-06
speciesLactobacillus_plantarum-0.1111.52e-062.9e-06
speciesMegamonas_hypermegale0.111.69e-063.22e-06
genusParvimonas-0.111.79e-063.38e-06
speciesBlautia_hydrogenotrophica-0.111.79e-063.38e-06
speciesParvimonas_unclassified-0.111.82e-063.42e-06
speciesBifidobacterium_bifidum-0.111.85e-063.47e-06
speciesDialister_invisus-0.111.94e-063.62e-06
speciesTuricibacter_unclassified-0.1092.19e-064.07e-06
speciesVeillonella_atypica0.1092.56e-064.74e-06
speciesPeptostreptococcaceae_noname_unclassified-0.1073.19e-065.86e-06
speciesBacteroides_clarus0.1073.19e-065.86e-06
speciesEnterococcus_faecalis-0.1073.38e-066.18e-06
speciesClostridium_sp_ATCC_BAA_4420.1073.45e-066.29e-06
familyAcidaminococcaceae-0.1073.71e-066.74e-06
speciesLactobacillus_gasseri-0.1064.21e-067.61e-06
speciesStreptococcus_pasteurianus0.1064.31e-067.76e-06
speciesRuminococcus_callidus-0.1055.02e-069.01e-06
speciesSubdoligranulum_sp_4_3_54A2FAA-0.1055.15e-069.21e-06
genusOxalobacter-0.1055.79e-061.03e-05
speciesOxalobacter_formigenes-0.1055.79e-061.03e-05
speciesMitsuokella_multacida-0.1055.8e-061.03e-05
familyOxalobacteraceae-0.1046.54e-061.15e-05
genusClostridiaceae_noname0.1029.49e-061.66e-05
speciesClostridiaceae_bacterium_JC1180.1029.49e-061.66e-05
genusRuminococcaceae_noname-0.1029.61e-061.67e-05
speciesRuminococcaceae_bacterium_D16-0.1029.61e-061.67e-05
speciesAnaerostipes_unclassified0.11.43e-052.47e-05
speciesStreptococcus_mitis_oralis_pneumoniae-0.0991.65e-052.84e-05
speciesCoprobacillus_unclassified0.0982.02e-053.47e-05
speciesGemella_morbillorum-0.0982.27e-053.88e-05
speciesSutterella_parvirubra0.0972.63e-054.48e-05
speciesClostridium_spiroforme-0.0963.08e-055.23e-05
speciesLactobacillus_ruminis-0.0953.66e-056.19e-05
speciesEggerthella_sp_1_3_56FAA-0.0953.77e-056.36e-05
speciesAggregatibacter_segnis0.0944.37e-057.34e-05
genusSutterellaceae_unclassified0.0944.44e-057.43e-05
speciesErysipelotrichaceae_bacterium_2_2_44A-0.0935.14e-058.57e-05
familyOscillospiraceae0.0935.45e-059.03e-05
genusOscillibacter0.0935.45e-059.03e-05
speciesBacteroides_cellulosilyticus0.0936.04e-059.97e-05
genusActinobacillus0.0926.81e-050.000112
speciesActinobacillus_unclassified0.0926.81e-050.000112
classGammaproteobacteria0.0918.79e-050.000144
genusPorphyromonas-0.099.3e-050.000151
orderPseudomonadales-0.0890.0001180.000191
speciesClostridium_clostridioforme0.0890.0001260.000204
speciesMegamonas_funiformis0.0880.000130.000209
speciesDesulfovibrio_piger-0.0880.000130.000209
speciesPorphyromonas_asaccharolytica-0.0870.0001710.000274
speciesCampylobacter_concisus0.0870.0001780.000284
speciesBacteroides_sp_3_1_190.0850.0002190.000348
speciesLactococcus_phage_jm2-0.0850.0002290.000363
speciesLactobacillus_amylovorus-0.0840.0002580.000407
genusButyricimonas0.0840.0002740.00043
speciesButyricimonas_synergistica0.0840.0002740.00043
speciesEubacterium_cylindroides-0.0840.000280.000438
speciesEubacterium_limosum-0.0830.0003090.000481
speciesOscillibacter_sp_KLE_17450.0820.0004060.00063
speciesEubacterium_dolichum0.0810.0004780.00074
speciesLachnospiraceae_bacterium_8_1_57FAA-0.0810.0004810.000742
speciesStreptococcus_australis-0.080.0005450.000838
speciesDorea_unclassified0.080.0005550.000851
speciesAcidaminococcus_fermentans-0.0790.0005980.000913
genusDesulfovibrio-0.0790.0006390.000973
genusC2likevirus-0.0770.0008750.00133
speciesLachnospiraceae_bacterium_1_4_56FAA0.0760.0009390.00142
speciesC2likevirus_unclassified-0.0760.0009920.0015
speciesBifidobacterium_angulatum-0.0760.001040.00156
speciesMegasphaera_elsdenii-0.0750.001240.00186
genusPeptostreptococcus-0.0740.00130.00194
speciesOscillibacter_unclassified0.0740.001420.00211
genusCoprobacillus0.0730.001530.00227
speciesCollinsella_tanakaei0.070.002610.00386
speciesPeptostreptococcus_stomatis-0.0690.002890.00426
speciesCollinsella_intestinalis0.0690.002990.0044
speciesOdoribacter_laneus-0.0680.003120.00457
speciesLactococcus_phage_phi7-0.0670.003540.00517
speciesLachnospiraceae_bacterium_7_1_58FAA-0.0670.003570.0052
genusMegasphaera0.0660.004080.00593
speciesHaemophilus_sputorum0.0660.00420.00608
speciesAlistipes_sp_AP11-0.0650.004860.00702
speciesHaemophilus_paraphrohaemolyticus0.0650.00510.00734
speciesLactobacillus_acidophilus-0.0640.005380.00772
orderViruses_noname-0.0640.005760.00824
speciesPorphyromonas_uenonis-0.0630.00660.00941
speciesAnaerotruncus_colihominis0.0610.007890.0112
speciesBifidobacterium_pseudocatenulatum0.0610.008020.0114
speciesBifidobacterium_breve-0.0610.008060.0114
speciesLactococcus_garvieae-0.0610.00820.0116
speciesParaprevotella_unclassified-0.0610.008390.0118
genusParaprevotella-0.060.009840.0138
speciesEscherichia_coli0.0590.01040.0145
speciesButyrivibrio_unclassified-0.0590.01050.0146
genusEscherichia0.0580.01160.0161
orderEnterobacteriales0.0570.01330.0184
familyEnterobacteriaceae0.0570.01330.0184
speciesLactobacillus_fermentum-0.0570.01360.0187
speciesOscillibacter_sp_KLE_17280.0560.01480.0203
familyRikenellaceae0.0560.01570.0214
genusAlistipes0.0560.01570.0214
speciesHoldemania_filiformis-0.0550.01670.0227
speciesParabacteroides_sp_D13-0.0540.0190.0258
speciesKlebsiella_oxytoca-0.0540.01970.0266
speciesPeptostreptococcus_anaerobius-0.0520.02440.0329
speciesParaprevotella_clara-0.0520.02460.0331
speciesAlistipes_shahii0.0510.0260.0349
speciesEnterobacter_aerogenes0.050.02960.0396
speciesPrevotella_copri-0.050.03140.0419
speciesRoseburia_intestinalis0.0480.03870.0515
speciesAlistipes_indistinctus-0.0470.04320.0573
speciesClostridium_ramosum0.0460.04440.0587
speciesBacteroides_sp_4_3_47FAA0.0460.04750.0626
speciesBacteroides_eggerthii0.0440.05720.0752
speciesClostridium_perfringens0.0430.06070.0796
speciesEubacterium_sp_3_1_310.0430.0620.0811
speciesEnterobacteria_phage_HK5440.0430.06460.0842
speciesFusobacterium_nucleatum0.0420.06980.0908
speciesLactobacillus_salivarius0.0420.07220.0936
speciesAlistipes_putredinis0.0410.07560.0978
speciesLactobacillus_reuteri-0.0410.07620.0983
familyClostridiaceae0.040.08170.105
classEpsilonproteobacteria0.040.08490.109
orderCampylobacterales0.040.08490.109
speciesPrevotella_bivia0.040.08660.11
speciesLactobacillus_vaginalis-0.040.08670.11
genusClostridium0.0390.09410.119
genusPyramidobacter0.0390.09510.12
speciesPyramidobacter_piscolens0.0390.09510.12
genusCampylobacter0.0380.0980.123
genusSlackia-0.0380.1040.131
speciesHoldemania_sp_AP20.0370.1070.134
genusAcidaminococcus-0.0370.1140.142
speciesLactobacillus_sanfranciscensis-0.0360.1180.147
speciesBacteroides_fluxus0.0350.1290.16
familyCampylobacteraceae0.0350.1310.162
speciesBacteroides_coprophilus0.0350.1340.166
genusEnterobacter0.0340.140.173
speciesWeissella_cibaria-0.0340.1440.177
genusStaphylococcus-0.0340.1480.181
familyPrevotellaceae-0.0330.1490.182
genusLambdalikevirus-0.0330.1520.185
speciesCollinsella_unclassified0.0330.1550.189
genusFaecalibacterium-0.0330.1590.192
speciesFaecalibacterium_prausnitzii-0.0330.1590.192
speciesHoldemania_unclassified-0.0320.1620.196
genusButyricicoccus0.0320.1710.205
speciesButyricicoccus_pullicaecorum0.0320.1710.205
phylumSynergistetes0.030.1890.224
classSynergistia0.030.1890.224
orderSynergistales0.030.1890.224
familySynergistaceae0.030.1890.224
speciesBacteroides_barnesiae0.030.1890.224
speciesCitrobacter_unclassified0.030.1950.231
genusPeptoniphilus-0.0290.2040.241
speciesCoprobacillus_sp_29_1-0.0290.2140.252
familyVeillonellaceae0.0280.2190.257
genusCoprobacter-0.0280.2210.258
speciesCoprobacter_fastidiosus-0.0280.2210.258
speciesErysipelotrichaceae_bacterium_3_1_530.0280.2220.259
speciesLactobacillus_crispatus-0.0280.2330.271
speciesEnterobacter_cloacae0.0270.2360.274
speciesStreptococcus_infantarius0.0270.2410.279
speciesOdoribacter_unclassified-0.0270.2420.279
genusMorganella0.0260.260.299
speciesMorganella_morganii0.0260.260.299
speciesLactobacillus_oris-0.0260.2660.305
genusHoldemania-0.0260.2670.305
familyStaphylococcaceae-0.0260.270.308
speciesLeuconostoc_lactis-0.0250.2790.317
familyMyoviridae0.0250.2820.32
speciesCitrobacter_freundii0.0240.2910.329
speciesAlistipes_sp_HGB5-0.0240.2920.33
speciesSlackia_piriformis-0.0240.3010.339
genusAcidaminococcaceae_unclassified0.0230.3150.354
speciesCoprobacillus_sp_D6-0.0230.320.359
speciesClostridium_sp_KLE_1755-0.0230.330.369
genusCitrobacter0.0220.3340.373
speciesParaprevotella_xylaniphila-0.0220.3380.376
speciesEggerthella_unclassified0.0220.3430.381
speciesDesulfovibrio_desulfuricans-0.0220.3480.386
speciesSutterella_wadsworthensis-0.0220.3520.389
familyViruses_noname-0.0210.3690.406
genusViruses_noname-0.0210.3690.406
classNegativicutes-0.0190.4090.448
orderSelenomonadales-0.0190.4090.448
genusProteus-0.0190.4110.449
genusMyoviridae_noname0.0180.4240.462
speciesBacteroides_sp_1_1_60.0170.4690.51
speciesEubacterium_eligens-0.0170.4730.513
speciesAlistipes_unclassified-0.0150.5090.551
speciesAcidaminococcus_intestini0.0140.5320.575
speciesKlebsiella_sp_MS_92_30.0140.5570.6
genusWeissella-0.0140.5590.601
speciesAlistipes_onderdonkii-0.0130.5720.614
speciesKlebsiella_unclassified0.0130.5810.622
speciesBlautia_producta-0.0120.6080.649
speciesEscherichia_unclassified-0.0120.6120.652
speciesLactobacillus_mucosae-0.0110.6230.662
speciesLactococcus_phage_936_sensu_lato-0.0110.6250.663
familySuccinivibrionaceae-0.010.6560.694
speciesAcidaminococcus_unclassified-0.010.6630.7
orderAeromonadales0.010.670.706
speciesStreptococcus_lutetiensis0.0090.6850.72
familyPodoviridae0.0090.6930.727
speciesBacteroides_salanitronis0.0080.7160.749
speciesLachnospiraceae_bacterium_1_1_57FAA-0.0080.7370.77
speciesAlistipes_finegoldii0.0080.7390.77
speciesProteus_mirabilis-0.0070.7540.783
speciesLactococcus_phage_bIL670.0070.7550.783
genusSuccinatimonas-0.0070.760.785
speciesSuccinatimonas_hippei-0.0070.760.785
speciesMegasphaera_unclassified0.0070.7650.788
speciesKlebsiella_phage_KP36-0.0070.770.792
genusEggerthella0.0070.7730.793
speciesCoriobacteriaceae_bacterium_phI-0.0060.7830.802
genusCoriobacteriaceae_noname-0.0060.7890.806
genusPrevotella-0.0060.8060.822
speciesWeissella_confusa-0.0050.8150.829
speciesErysipelotrichaceae_bacterium_5_2_54FAA0.0050.8320.845
speciesParabacteroides_sp_20_3-0.0050.8340.845
speciesStreptococcus_phage_Sfi21-0.0050.840.849
genusPantoea0.0030.8950.901
speciesPantoea_unclassified0.0030.8950.901
genusSutterella-0.0030.9120.916
genusTunalikevirus-0.0030.9140.916
speciesLachnospiraceae_bacterium_5_1_57FAA0.0020.9280.928
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Association of query gene abundance with clinical phenotypes:

Boxplots:


Statistics:

pheno country case_n ctrl_n case_mean ctrl_mean pvalue rank percentile
Crohns diseaseSpain17660.2072742678360.1206724607550.000439924584915323710.7631
Type II diabetesChina1831850.1756165007260.1994284368410.0419633995331652221.5539
ObesityDenmark1691230.1149330217080.09710100799810.125608137688839827.615
Type II diabetesDenmark752770.09403764579090.1080143080810.1540179853721154937.8569
Rheumatoid arthritisChina127980.1150246810380.1299095351840.3457357740851329044.3192
Colorectal cancerAustria64350.02894127588740.02537522346550.3979023699371496350.6259
Liver cirrhosisChina1201140.2169027046470.2269816967950.5635820368512504384.1244
Ulcerative colitisSpain78660.1129609966940.1206724607550.6156541762662194772.3989
Type II diabetesSweden53920.04692401315310.04132519187930.987925447992913098.6454
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Citation:

Nayfach S, Fischbach MA, Pollard KS. MetaQuery: a web server for rapid annotation and quantitative analysis of specific genes in the human gut microbiome. Bioinformatics 2015;31(14). doi:10.1093/bioinformatics/btv382