Estimated abundances and results from statistical analyses
Query type: function
Description: E22.214.171.124, adh; alcohol dehydrogenase [EC:126.96.36.199]
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The abundance of K00001 across gut microbiome samples:
For taxonomic groups (e.g. species), abundance is defined as the proportion of cells that are from a taxonomic group
For functional groups (e.g. gene families), abundance is defined as the average copy-number of the function per cell
the abundance of K00001 was estimated across human gut metagenomes
Samples with an abundance of zero were assigned the smallest non-zero value
the average abundance of K00001 was compared to the average abundance
of other groups at the same functional or taxonomic level
The prevalence of K00001 across gut microbiome samples:
is defined at the percent of samples where K00001 is found
the prevalence of K00001 was estimated across human gut metagenomes at different abundance thresholds
the prevalence of K00001 at a minimum abundance of 0.001 was compared to the prevalence
of other groups at the same functional or taxonomic level.
Association of K00001 abundance with clinical phenotypes:
Wilcoxon rank-sum tests
were performed to determine if the abundance of K00001 was different between cases and controls for several diseases (see table)
For each disease, case and control individuals were selected from the same country and individuals with co-morbities were excluded
See the documentation for more information on these cohorts
p_value indicates whether there is a significant difference in the abundance of K00001 between cases and controls
rank and percentile indicate how the p_value for K00001 compares to other functional or taxonomic groups
For example, a percentile of 5.0 indicates your p_value was more significant than 95% of other functions or taxa
| pheno || country || case_n || ctrl_n || case_mean || ctrl_mean || p_value || rank || percentile |
|Type II diabetes||China||183||185||0.591430168643||0.522705721895||0.00418135489826||869||12.9682|
|Type II diabetes||Denmark||75||277||0.437451440295||0.40839414075||0.0652846711163||2989||44.3925|
|Type II diabetes||Sweden||53||92||0.483383405954||0.472217935687||0.383423235372||2817||42.2201|
Click on arrows to sort table data. Shift+click to sort by multiple columns.
Nayfach S, Fischbach MA, Pollard KS.
MetaQuery: a web server for rapid annotation and quantitative analysis of specific genes in the human gut microbiome.